| Tdark | Flt3-interacting zinc finger protein 1 |
May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity).
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008]
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 1.4e-08 |
| atypical teratoid / rhabdoid tumor | 5112 | 4.2e-08 |
| glioblastoma | 5792 | 5.7e-08 |
| osteosarcoma | 7950 | 6.0e-08 |
| medulloblastoma, large-cell | 6241 | 2.6e-06 |
| group 4 medulloblastoma | 1855 | 1.1e-04 |
| Disease | log2 FC | p |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 1.400 | 4.2e-08 |
| glioblastoma | 1.300 | 5.7e-08 |
| group 4 medulloblastoma | 1.100 | 1.1e-04 |
| medulloblastoma, large-cell | 1.400 | 2.6e-06 |
| osteosarcoma | 1.919 | 6.0e-08 |
| ovarian cancer | 1.100 | 1.4e-08 |
MDDVPAPTPAPAPPAAAAPRVPFHCSECGKSFRYRSDLRRHFARHTALKPHACPRCGKGFKHSFNLANHL 1 - 70 RSHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVCELRFSSRSSLGRHLKRQHRGVLPSPLQP 71 - 140 GPGLPALSAPCSVCCNVGPCSVCGGSGAGGGEGPEGAGAGLGSWGLAEAAAAAAASLPPFACGACARRFD 141 - 210 HGRELAAHWAAHTDVKPFKCPRCERDFNAPALLERHKLTHDLQGPGAPPAQAWAAGPGAGPETAGEGTAA 211 - 280 EAGDAPLASDRRLLLGPAGGGVPKLGGLLPEGGGEAPAPAAAAEPSEDTLYQCDCGTFFASAAALASHLE 281 - 350 AHSGPATYGCGHCGALYAALAALEEHRRVSHGEGGGEEAATAAREREPASGEPPSGSGRGKKIFGCSECE 351 - 420 KLFRSPRDLERHVLVHTGEKPFPCLECGKFFRHECYLKRHRLLHGTERPFPCHICGKGFITLSNLSRHLK 421 - 490 LHRGMD 491 - 496 //
