Property Summary

Ligand Count 2,718
NCBI Gene PubMed Count 1,322
PubMed Score 33691.43
PubTator Score 17181.64

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (6)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.9
Disease Target Count Z-score Confidence
Liver disease 237 6.982 3.5
Vitamin K deficiency hemorrhagic disease 11 6.35 3.2
Antiphospholipid syndrome 19 6.222 3.1
Thrombocytopenia 197 5.907 3.0
Blood protein disease 11 5.892 2.9
Protein C deficiency 19 5.84 2.9
Hepatic encephalopathy 27 5.834 2.9
Cancer 2499 5.83 2.9
Cerebrovascular disease 238 5.578 2.8
Atrial Fibrillation 124 5.54 2.8
Portal vein thrombosis 12 5.245 2.6
Esophageal varix 12 5.133 2.6
Hepatitis B 108 5.117 2.6
Coronary artery disease 268 5.11 2.6
Factor VII Deficiency 7 5.034 2.5
Factor X Deficiency 6 5.021 2.5
Hyperhomocysteinemia 37 4.991 2.5
Portal hypertension 20 4.903 2.5
Varicose veins 20 4.9 2.4
Antithrombin III deficiency 14 4.88 2.4
Budd-Chiari syndrome 12 4.877 2.4
Lupus erythematosus 57 4.834 2.4
Hemophilia B 11 4.765 2.4
Kidney disease 430 4.669 2.3
Placental abruption 18 4.643 2.3
Hypertension 396 4.625 2.3
Factor V deficiency 8 4.589 2.3
Factor XI Deficiency 12 4.488 2.2
Anemia 365 4.46 2.2
Von Willebrand's disease 19 4.444 2.2
Cholestasis 155 4.371 2.2
Connective tissue disease 62 4.237 2.1
Hypochondriasis 6 4.225 2.1
Hepatitis A 11 4.199 2.1
Bilirubin metabolic disorder 41 4.161 2.1
Thrombophlebitis 19 4.142 2.1
Peripheral vascular disease 87 4.12 2.1
Hepatitis C 94 4.096 2.0
Lung disease 142 4.001 2.0
diabetes mellitus 1728 3.826 1.9
Factor XIII deficiency 6 3.812 1.9
Purpura 43 3.81 1.9
Hypersplenism 10 3.795 1.9
Peritonitis 43 3.781 1.9
Factor VIII deficiency 10 3.755 1.9
Autoimmune hepatitis 11 3.661 1.8
Endocarditis 19 3.607 1.8
Cholangitis 32 3.483 1.7
Diarrhea 253 3.471 1.7
Vasculitis 80 3.467 1.7
post-thrombotic syndrome 7 3.451 1.7
Atherosclerosis 291 3.429 1.7
Congenital heart disease 93 3.428 1.7
Crimean-Congo hemorrhagic fever 9 3.418 1.7
Congenital afibrinogenemia 11 3.401 1.7
Leukopenia 72 3.392 1.7
Skin disease 66 3.365 1.7
Heart valve disease 39 3.344 1.7
Asthma 385 3.232 1.6
Lactic acidosis 51 3.216 1.6
Factor XII deficiency 13 3.192 1.6
Transient Cerebral Ischemia 25 3.145 1.6
Glanzmann's thrombasthenia 23 3.112 1.6
Congestive heart failure 113 3.093 1.5
Pancreatitis 123 3.021 1.5
Active peptic ulcer disease 3 3.007 1.5
Schistosomiasis 35 3.003 1.5

Expression

Synonym

Accession P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1
Symbols PT
THPH1
RPRGL2

Gene

F2

PANTHER Protein Class (3)

PDB

3QDZ   1SR5   1TB6   2B5T   1NY2   1NRN   1NRO   1NRP   1NRQ   1NRR   3BEF   3HKJ   3LU9   3P6Z   3P70   2A45   2HWL   1DM4   1FPH   1A2C   1A3B   1A3E   1A46   1A4W   1A5G   1A61   1ABI   1ABJ   1AD8   1AE8   1AFE   1AHT   1AI8   1AIX   1AWF   1AWH   1AY6   1B5G   1B7X   1BA8   1BB0   1BCU   1BHX   1BMM   1BMN   1BTH   1C1U   1C1V   1C1W   1C4U   1C4V   1C4Y   1C5L   1C5N   1C5O   1CA8   1D3D   1D3P   1D3Q   1D3T   1D4P   1D6W   1D9I   1DE7   1DIT   1DOJ   1DWB   1DWC   1DWD   1DWE   1DX5   1E0F   1EB1   1EOJ   1EOL   1FPC   1G30   1G32   1G37   1GHV   1GHW   1GHX   1GHY   1GJ4   1GJ5   1H8D   1H8I   1HAG   1HAH   1HAI   1HAO   1HAP   1HBT   1HDT   1HGT   1HLT   1HUT   1HXE   1HXF   1IHS   1IHT   1JMO   1JOU   1JWT   1K21   1K22   1KTS   1KTT   1LHC   1LHD   1LHE   1LHF   1LHG   1MH0   1MU6   1MU8   1MUE   1NM6   1NO9   1NRS   1NT1   1NU7   1NU9   1NZQ   1O0D   1O2G   1O5G   1OOK   1OYT   1P8V   1PPB   1QBV   1QHR   1QJ1   1QJ6   1QJ7   1QUR   1RD3   1RIW   1SB1   1SFQ   1SG8   1SGI   1SHH   1SL3   1T4U   1T4V   1TA2   1TA6   1TBZ   1THP   1THR   1THS   1TMB   1TMT   1TMU   1TOM   1TQ0   1TQ7   1TWX   1UMA   1UVS   1VR1   1VZQ   1W7G   1WAY   1WBG   1XM1   1XMN   1YPE   1YPG   1YPJ   1YPK   1YPL   1YPM   1Z71   1Z8I   1Z8J   1ZGI   1ZGV   1ZRB   2A0Q   2A2X   2AFQ   2ANK   2ANM   2BDY   2BVR   2BVS   2BVX   2BXT   2BXU   2C8W   2C8X   2C8Y   2C8Z   2C90   2C93   2CF8   2CF9   2CN0   2FEQ   2FES   2GDE   2GP9   2H9T   2HGT   2HNT   2HPP   2HPQ   2JH0   2JH5   2JH6   2OD3   2PGB   2PGQ   2PKS   2PW8   2R2M   2THF   2UUF   2UUJ   2UUK   2V3H   2V3O   2ZC9   2ZDA   2ZDV   2ZF0   2ZFF   2ZFP   2ZFQ   2ZFR   2ZG0   2ZGB   2ZGX   2ZHE   2ZHF   2ZHQ   2ZHW   2ZI2   2ZIQ   2ZNK   2ZO3   3B23   3B9F   3BEI   3BF6   3BIU   3BIV   3BV9   3C1K   3C27   3D49   3DA9   3DD2   3DHK   3DT0   3DUX   3E6P   3EE0   3EGK   3EQ0   3F68   3GIC   3GIS   3HAT   3HTC   3JZ1   3JZ2   3K65   3LDX   3NXP   3P17   3PMH   3PO1   3QGN   3QLP   3QTO   3QTV   3QWC   3QX5   3R3G   3RLW   3RLY   3RM0   3RM2   3RML   3RMM   3RMN   3RMO   3S7H   3S7K   3SHA   3SHC   3SI3   3SI4   3SQE   3SQH   3SV2   3T5F   3TU7   3U69   3U8O   3U8R   3U8T   3U98   3U9A   3UTU   3UWJ   3VXE   3VXF   4AX9   4AYV   4AYY   4AZ2   4BAH   4BAK   4BAM   4BAN   4BAO   4BAQ   4BOH   4CH2   4CH8   4DIH   4DII   4DT7   4DY7   4E05   4E06   4E7R   4H6S   4H6T   4HFP   4HTC   4HZH   4I7Y   4LOY   4LXB   4LZ1   4LZ4   4MLF   4N3L   4NZE   4NZQ   4O03   4RKJ   4RKO   4RN6   4THN   4UD9   4UDW   4UE7   4UEH   4UFD   4UFE   4UFF   4UFG   4YES   5A2M   5AF9   5AFY   5AFZ   5AHG   5CMX   5DO4   5E8E   5EDK   5EDM   5EW1   5EW2   5GDS   5GIM   5JDU   5JFD   5JZY   5L6N   5NHU   5TO3   6EO6   6EO7   7KME   8KME  

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

Gene RIF (1274)

AA Sequence

MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEA      1 - 70
FEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKP     71 - 140
EINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPL    141 - 210
EQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKP    211 - 280
GDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDK    281 - 350
TERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN    351 - 420
DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAA    421 - 490
SLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKR    491 - 560
GDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE            561 - 622
//

Text Mined References (1340)

PMID Year Title