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Tchem
CPT1B
Carnitine O-palmitoyltransferase 1, muscle isoform

Protein Summary
Description
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312108
  • ENSP00000312189
  • ENSG00000205560
  • ENST00000360719
  • ENSP00000353945
  • ENST00000395650
  • ENSP00000379011
  • ENST00000405237
  • ENSP00000385486
  • ENST00000457250
  • ENSP00000409342

Symbol
  • KIAA1670
  • CPTI
  • CPT1M
  • MCPT1
  • CPT1-M
  • CPTI-M
  • M-CPT1
  • MCCPT1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
metabolite
1
virus perturbation
0.99
cellular component
0.86
disease
0.6
biological process
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 155.12   (req: < 5)
Gene RIFs: 31   (req: <= 3)
Antibodies: 364   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 155.12   (req: >= 5)
Gene RIFs: 31   (req: > 3)
Antibodies: 364   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 50
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0