| Tbio | C-type lectin domain family 17, member A |
Cell surface receptor which may be involved in carbohydrate-mediated communication between cells in the germinal center. Binds glycans with terminal alpha-linked mannose or fucose residues.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6685 | 3.0e-10 |
| facioscapulohumeral dystrophy | 286 | 1.3e-08 |
| Disease | log2 FC | p |
|---|---|---|
| psoriasis | 2.000 | 3.0e-10 |
| facioscapulohumeral dystrophy | 3.600 | 1.3e-08 |
| PMID | Text | |
|---|---|---|
| 19419970 | this novel receptor has the potential to function in carbohydrate-mediated communication between cells in the germinal center |
MHNLYSITGYPDPPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGTME 1 - 70 EEEEDDDYENSTPPYKDLPPKPGSSAPPRPPRAAKETEKPPLPCKPRNMTGLDLAAVTCPPPQLAVNLEP 71 - 140 SPLQPSLAATPVPWLNQRSGGPGCCQKRWMVYLCLLVVTSLFLGCLGLTVTLIKYQELMEELRMLSFQQM 141 - 210 TWRTNMTGMAGLAGLKHDIARVRADTNQSLVELWGLLDCRRITCPEGWLPFEGKCYYFSPSTKSWDEARM 211 - 280 FCQENYSHLVIINSFAEHNFVAKAHGSPRVYWLGLNDRAQEGDWRWLDGSPVTLSFWEPEEPNNIHDEDC 281 - 350 ATMNKGGTWNDLSCYKTTYWICERKCSC 351 - 378 //
| PMID | Year | Title | |
|---|---|---|---|
| 23453885 | 2013 | Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. | |
| 19419970 | 2009 | Prolectin, a glycan-binding receptor on dividing B cells in germinal centers. | |
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | |
| 15057824 | 2004 | The DNA sequence and biology of human chromosome 19. | |
| 14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. | |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
