Tbio ARHGAP30 Rho GTPase-activating protein 30

Protein Summary

Description

GTPase-activating protein (GAP) for RAC1 and RHOA, but not for CDC42.

Uniprot Accession IDs

• Q7Z6I6
• Q5SY52
• Q5SY53
• Q5SY54
• Q6ZML6
• Q7Z3J8
• Q86XI7

Gene Name

• ARHGAP30

Ensembl ID

• ENST00000368013
• ENSP00000356992
• ENSG00000186517

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
drug perturbation	0.87
tissue sample	0.78
virus perturbation	0.76
cell type or tissue	0.72
kinase perturbation	0.6

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.47   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 91   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.47   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0