Property Summary

NCBI Gene PubMed Count 18
PubMed Score 1.94
PubTator Score 1.33

Knowledge Summary


No data available


  Differential Expression (6)

Disease log2 FC p
osteosarcoma -1.513 2.2e-03
posterior fossa group B ependymoma 2.100 2.3e-09
lung adenocarcinoma -1.500 1.4e-13
non-small cell lung carcinoma -1.300 3.0e-16
chronic rhinosinusitis -1.309 2.1e-02
cystic fibrosis and chronic rhinosinusit... -1.498 2.3e-02

Gene RIF (7)

25855136 rs13014235 is associated with susceptibility to cutaneous basal cell carcinoma.
25168388 Genome-wide association studies show a significant association between the intronic SNP rs1830298 in ALS2CR12 gene and breast cancer; further expression studies suggest that CASP8 might be the target gene.
21048031 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19773279 Observational study of gene-disease association. (HuGE Navigator)
19692168 Observational study of gene-disease association. (HuGE Navigator)
18649358 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

RLASITVSKDDSDTVQDGSKKGQES                                                 421 - 445

Text Mined References (21)

PMID Year Title
25855136 2015 New basal cell carcinoma susceptibility loci.
25416956 2014 A proteome-scale map of the human interactome network.
25168388 2015 Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.
25129146 2014 Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations.
24390342 2014 Genetics of rheumatoid arthritis contributes to biology and drug discovery.
21983787 2011 Genome-wide association study identifies three new melanoma susceptibility loci.
21048031 2011 Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
19773279 2009 Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
19692168 2010 Genetic susceptibility to distinct bladder cancer subphenotypes.
19608861 2009 Lysine acetylation targets protein complexes and co-regulates major cellular functions.
19060904 2009 An empirical framework for binary interactome mapping.
18649358 2008 Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.
17474147 2007 Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
15815621 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11586298 2001 A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.
8889548 1996 Normalization and subtraction: two approaches to facilitate gene discovery.