Development Level

Tbio 11,178
Tdark 6,569
Tchem 1,885
Tclin 612

Collection

GPCR: IDG Consortium (Targets) 126
Kinase: IDG Consortium (Target... 125
Ion Channel: IDG Consortium (T... 99
Kinase: IDG Consortium (Comple... 37
GPCR: IDG Consortium (Complete... 25

IMPC Phenotype

preweaning lethality, complete... 979
preweaning lethality, incomple... 499
abnormal behavior 298
embryonic lethality prior to t... 278
embryonic lethality prior to o... 239
abnormal embryo size 220
enlarged heart 210
decreased vertical activity 208
decreased total body fat amoun... 207
abnormal bone structure 187
increased lean body mass 172
abnormal heart morphology 162
decreased body weight 161
decreased bone mineral content 151
hyperactivity 148
decreased lean body mass 135
increased total body fat amoun... 134
hypoactivity 132
decreased circulating glucose ... 126
decreased bone mineral density 126
male infertility 123
increased circulating alkaline... 122
decreased grip strength 116
abnormal seminal vesicle morph... 114
increased startle reflex 112
increased bone mineral content 108
embryonic growth retardation 106
increased or absent threshold ... 101
decreased body length 101
short tibia 97
increased mean corpuscular hem... 96
decreased circulating choleste... 93
increased mean corpuscular vol... 92
cataract 92
prenatal lethality prior to he... 87
decreased lymphocyte cell numb... 83
decreased prepulse inhibition 82
decreased circulating serum al... 82
abnormal lens morphology 81
increased circulating HDL chol... 80
decreased mean corpuscular vol... 79
improved glucose tolerance 79
decreased circulating triglyce... 79
decreased circulating insulin ... 76
increased fasted circulating g... 76
decreased startle reflex 75
impaired glucose tolerance 75
small superior vagus ganglion 74
decreased leukocyte cell numbe... 73
increased bone mineral density 72
increased circulating sodium l... 71
abnormal retina morphology 71
abnormal sleep behavior 70
abnormal gait 69
abnormal eye morphology 68
decreased circulating HDL chol... 68
decreased hemoglobin content 68
increased circulating choleste... 66
abnormal behavioral response t... 66
abnormal kidney morphology 65
decreased fasted circulating g... 65
abnormal coat-hair pigmentatio... 64
increased monocyte cell number 63
increased heart weight 62
decreased erythrocyte cell num... 62
female infertility 60
edema 59
small testis 58
thrombocytopenia 56
abnormal spleen morphology 55
decreased caudal vertebrae num... 53
hydrometra 53
decreased blood urea nitrogen ... 51
decreased mean corpuscular hem... 50
abnormal skin morphology 50
decreased circulating total pr... 49
increased blood urea nitrogen ... 48
decreased circulating alanine ... 47
increased leukocyte cell numbe... 47
increased neutrophil cell numb... 46
decreased circulating alkaline... 46
increased hematocrit 46
decreased hematocrit 46
abnormal neural tube closure 46
increased hemoglobin content 45
increased mean platelet volume 45
abnormal testis morphology 43
abnormal epididymis morphology 42
decreased neutrophil cell numb... 42
increased circulating triglyce... 42
increased grip strength 41
increased circulating chloride... 41
enlarged spleen 41
decreased red blood cell distr... 41
limb grasping 41
increased erythrocyte cell num... 39
decreased circulating creatini... 39
tremors 39
prolonged QT interval 38
abnormal bone mineralization 38

Disease

Carcinoma 11,192
ovarian cancer 8,297
osteosarcoma 7,766
psoriasis 6,514
medulloblastoma, large-cell 6,086
glioblastoma 5,635
atypical teratoid / rhabdoid tumor 4,971
lung cancer 4,607
ependymoma 4,559
group 3 medulloblastoma 4,002
adult high grade glioma 3,701
Breast cancer 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204
malignant mesothelioma 3,135
Astrocytoma, Pilocytic 3,006
primitive neuroectodermal tumor 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872
invasive ductal carcinoma 2,867
non-small cell lung cancer 2,799
oligodendroglioma 2,768
lung carcinoma 2,755
lung adenocarcinoma 2,627
Kidney cancer 2,548
astrocytic glioma 2,530
Cancer 2,388
pancreatic cancer 2,322
interstitial cystitis 2,237
subependymal giant cell astrocytoma 2,230
tuberculosis 1,963
pituitary cancer 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911
Pick disease 1,856
group 4 medulloblastoma 1,806
ulcerative colitis 1,765
ductal carcinoma in situ 1,686
diabetes mellitus 1,683
cystic fibrosis 1,629
breast carcinoma 1,589
colon cancer 1,428
Autosomal recessive predisposition 1,407
adrenocortical carcinoma 1,385
Multiple myeloma 1,296
Rheumatoid arthritis 1,156
juvenile dermatomyositis 1,147
Schizophrenia 1,136
acute quadriplegic myopathy 1,133
astrocytoma 1,113
primary pancreatic ductal adenocarcinoma 1,071
spina bifida 1,053
pediatric high grade glioma 1,035
nasopharyngeal carcinoma 1,024
cutaneous lupus erythematosus 1,016
Intellectual disability 998
dermatomyositis 941
Atopic dermatitis 915
active Crohn's disease 882
non primary Sjogren syndrome sicca 861
gastric carcinoma 781
Epilepsy 775
acute myeloid leukemia 760
Waldenstrons macroglobulinemia 742
active ulcerative colitis 736
Liver Cirrhosis, Experimental 733
primary Sjogren syndrome 710
medulloblastoma 702
esophageal adenocarcinoma 696
Melanoma 689
progressive supranuclear palsy 656
Obesity 655
Bipolar Disorder 646
aldosterone-producing adenoma 646
Alzheimer's disease 640
Mental Retardation 634
Low intelligence 634
Mental deficiency 634
Poor school performance 634
Dull intelligence 634
Global developmental delay 596
Cognitive delay 596
Mental and motor retardation 596
Liver cancer 589
Duchenne muscular dystrophy 587
Seizures 584
Muscle hypotonia 562
pancreatic carcinoma 555
fibroadenoma 538
hepatocellular carcinoma 536
Multiple Sclerosis 527
Endometriosis 521
Short stature 514
chronic rhinosinusitis 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492
Down syndrome 480
mucosa-associated lymphoid tissue lymphoma 473
Prostatic Neoplasms 472
sonic hedgehog group medulloblastoma 459
posterior fossa group A ependymoma 456
Skin cancer 451
gastric cancer 445

Tissue

Endocrine System 18,159
Female tissues 17,400
Digestive Tract 17,369
Skin and soft tissues 17,230
Male tissues 17,142
Blood and immune system 16,909
Liver and Pancreas 16,750
Nervous System 16,725
Urinary Tract 16,678
Respiratory system 16,393
Cardiovascular System 15,192

Target Family

Non-IDG 12,091
Enzyme 4,145
Transcription Factor 1,400
Kinase 634
Transporter 473
oGPCR 421
GPCR 408
Ion Channel 344
Epigenetic 242
Nuclear Receptor 48
TF/Epigenetic 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coiled-coil domain-containing protein 186 CCDC186 Tdark Non-IDG 1.85 0.01 15
Transcription elongation factor A N-terminal and central domain-containing protein 2 TCEANC2 Tdark Non-IDG 1.78 0.02 84
Zinc finger protein 773 ZNF773 Tdark Transcription Factor 1.78 0.02 108
Protein FAM153A FAM153A Tdark Non-IDG 1.72 0.02 12
Protein FAM153C FAM153C Tdark Non-IDG 1.72 0.02 6
Protein FAM117B FAM117B Tdark Non-IDG 1.63 0.11 76
Uncharacterized protein C2orf66 C2orf66 Tdark Non-IDG 1.62 0.02 7
Zinc finger protein 559 ZNF559 Tdark Transcription Factor 1.60 0.02 94
Uncharacterized protein C16orf90 C16orf90 Tdark Non-IDG 1.58 0.03 9
Protein FAM171A1 FAM171A1 Tdark Non-IDG 1.57 0.02 38