Development Level

Tbio 11,086
Tdark 7,031
Tchem 1,402
Tclin 601

Collection

Eligible non-olfactory GPCR Proteins 143
Eligible Kinase Proteins 134
Eligible Ion Channel Proteins 117

IMPC Term

preweaning lethality, complete... 633
preweaning lethality, incomple... 260
abnormal behavior 226
decreased lean body mass 195
embryonic lethality prior to t... 187
decreased total body fat amoun... 186
decreased body weight 174
decreased bone mineral content 157
embryonic lethality prior to o... 148
abnormal bone structure 131
increased or absent threshold ... 128
decreased bone mineral density 126
decreased grip strength 123
decreased circulating glucose ... 121
increased circulating alkaline... 119
abnormal embryo size 112
enlarged heart 111
hyperactivity 108
decreased body length 108
increased lean body mass 107
abnormal retina morphology 100
increased mean corpuscular hem... 93
increased bone mineral content 92
increased mean corpuscular vol... 91
hypoactivity 89
decreased circulating choleste... 85
increased grip strength 83
decreased circulating triglyce... 83
short tibia 82
decreased circulating serum al... 79
decreased circulating HDL chol... 77
decreased circulating insulin ... 75
abnormal lens morphology 73
increased circulating sodium l... 71
increased fasted circulating g... 68
prenatal lethality prior to he... 64
abnormal sleep behavior 63
increased circulating HDL chol... 63
male infertility 62
decreased lumbar vertebrae num... 62
increased sacral vertebrae num... 62
abnormal retinal pigmentation 61
decreased rib number 59
increased total body fat amoun... 57
improved glucose tolerance 56
increased exploration in new e... 56
abnormal bone mineralization 55
decreased leukocyte cell numbe... 54
abnormal coat/hair pigmentatio... 54
decreased circulating alanine ... 53
decreased hemoglobin content 53
increased circulating choleste... 53
decreased prepulse inhibition 52
impaired glucose tolerance 52
abnormal behavioral response t... 52
increased bone mineral density 52
abnormal gait 51
abnormal heart morphology 51
decreased mean corpuscular vol... 50
decreased fasted circulating g... 49
decreased caudal vertebrae num... 49
decreased startle reflex 48
abnormal seminal vesicle morph... 47
thrombocytopenia 46
increased hemoglobin content 45
decreased heart weight 44
increased blood urea nitrogen ... 44
decreased erythrocyte cell num... 43
increased circulating chloride... 43
increased body weight 42
decreased circulating alkaline... 41
decreased circulating total pr... 41
decreased eosinophil cell numb... 41
increased rib number 41
decreased circulating free fat... 39
increased startle reflex 38
abnormal eye morphology 38
decreased circulating LDL chol... 37
increased heart weight 37
small testis 37
decreased neutrophil cell numb... 37
abnormal neural tube closure 37
increased leukocyte cell numbe... 37
increased hematocrit 36
abnormal spleen morphology 36
cardiovascular system phenotyp... 35
limb grasping 35
tremors 34
female infertility 34
decreased mean corpuscular hem... 34
decreased circulating calcium ... 33
increased circulating calcium ... 32
abnormal cranium morphology 32
decreased circulating chloride... 32
decreased threshold for audito... 32
decreased circulating fructosa... 31
abnormal epididymis morphology 31
increased circulating potassiu... 31
decreased T cell number 31
decreased blood urea nitrogen ... 31

Disease

ovarian cancer 8,484
osteosarcoma 7,933
psoriasis 6,683
medulloblastoma, large-cell 6,234
glioblastoma 5,572
lung cancer 4,466
atypical teratoid / rhabdoid tumor 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289
malignant mesothelioma 3,162
Breast cancer 3,094
pilocytic astrocytoma 3,086
primitive neuroectodermal tumor 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956
invasive ductal carcinoma 2,950
oligodendroglioma 2,849
lung carcinoma 2,844
non-small cell lung cancer 2,798
lung adenocarcinoma 2,713
pediatric high grade glioma 2,712
ependymoma 2,514
Cancer 2,346
pancreatic cancer 2,300
interstitial cystitis 2,299
subependymal giant cell astrocytoma 2,287
group 3 medulloblastoma 2,254
astrocytic glioma 2,241
adult high grade glioma 2,148
Carcinoma 2,147
ulcerative colitis 2,085
pituitary cancer 1,972
Pick disease 1,893
group 4 medulloblastoma 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795
ductal carcinoma in situ 1,745
cystic fibrosis 1,665
diabetes mellitus 1,663
breast carcinoma 1,614
tuberculosis 1,557
posterior fossa group B ependymoma 1,530
medulloblastoma 1,524
posterior fossa group A ependymoma 1,511
astrocytoma 1,493
sonic hedgehog group medulloblastoma 1,482
colon cancer 1,475
adrenocortical carcinoma 1,427
Multiple myeloma 1,327
primary pancreatic ductal adenocarcinoma 1,271
juvenile dermatomyositis 1,189
Rheumatoid Arthritis 1,157
acute quadriplegic myopathy 1,157
atypical teratoid/rhabdoid tumor 1,095
spina bifida 1,064
cutaneous lupus erythematosus 1,056
nasopharyngeal carcinoma 1,056
Atopic dermatitis 942
dermatomyositis 933
active Crohn's disease 918
non primary Sjogren syndrome sicca 840
gastric carcinoma 832
primary Sjogren syndrome 789
acute myeloid leukemia 780
Waldenstrons macroglobulinemia 765
esophageal adenocarcinoma 737
tuberculosis and treatment for 6 months 686
progressive supranuclear palsy 674
aldosterone-producing adenoma 664
Alzheimer's disease 644
Obesity 616
Duchenne muscular dystrophy 602
Intellectual disability 573
pancreatic carcinoma 567
fibroadenoma 557
Down syndrome 548
Endometriosis 534
hepatocellular carcinoma 532
chronic rhinosinusitis 512
Schizophrenia 500
autosomal dominant Emery-Dreifuss muscular dystrophy 499
Multiple Sclerosis 496
mucosa-associated lymphoid tissue lymphoma 480
active ulcerative colitis 477
Prostatic Neoplasms 471
IGA Glomerulonephritis 454
Amyotrophic Lateral Sclerosis 431
gastric cancer 430
non-small cell lung carcinoma 413
Mammary Neoplasms 410
inflammatory breast cancer 404
Kidney disease 396
Neurodegenerative disease 383
Parkinson's disease 364
sarcoidosis 356
Asthma 347
glioblastoma multiforme 347
Epilepsy 346
Polycystic Ovary Syndrome 332
nephrosclerosis 329
tuberculosis and treatment for 3 months 327
Autistic Disorder 320

Tissue

Female tissues 18,647
Nervous System 18,561
Endocrine System 18,512
Digestive Tract 18,473
Urinary Tract 18,444
Liver and Pancreas 18,136
Skin and soft tissues 18,115
Blood and immune system 17,995
Male tissues 17,969
Cardiovascular System 17,958
Respiratory system 17,484

Target Family

Non-IDG 11,971
Enzyme 4,146
Transcription Factor 1,400
Kinase 634
Transporter 473
oGPCR 421
GPCR 406
Ion Channel 341
Epigenetic 242
Nuclear Receptor 48
TF/Epigenetic 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 773 ZNF773 Tdark Transcription Factor 1.76 0.02 92
Protein FAM153A FAM153A Tdark Non-IDG 1.71 0.02 7
Protein FAM153C FAM153C Tdark Non-IDG 1.71 0.02 2
Forkhead box protein D4-like 3 FOXD4L3 Tdark Transcription Factor 1.64 0.10 7
Uncharacterized protein C2orf66 C2orf66 Tdark Non-IDG 1.62 0.02 6
Coiled-coil domain-containing protein 190 CCDC190 Tdark Non-IDG 1.62 0.35 63
Zinc finger protein 559 ZNF559 Tdark Transcription Factor 1.60 0.02 73
Protein FAM171A1 FAM171A1 Tdark Non-IDG 1.57 0.02 35
Coiled-coil domain-containing protein 84 CCDC84 Tdark Non-IDG 1.53 0.02 43
Tubulin alpha-3E chain TUBA3E Tchem Non-IDG 1.49 0.03 27