troglitazone
Ligand Summary
A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
UNII: 1A70L3TM4P
PubChem: 5591
Guide to Pharmacology: 2693
ChEMBL: CHEMBL408
DrugCentral: 2767
LyCHI: ZZZKMSXJFFQN
Target Activities
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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EC50 | AGONIST | |||||