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atopic dermatitis 2
Disease Summary
Associated Targets (1)
Tbio
1
Mondo Description Any atopic eczema in which the cause of the disease is a mutation in the FLG gene.
Uniprot Description Atopic dermatitis is a complex, inflammatory disease with multiple alleles at several loci thought to be involved in the pathogenesis. It commonly begins in infancy or early childhood and is characterized by a chronic relapsing form of skin inflammation, a disturbance of epidermal barrier function that culminates in dry skin, and IgE-mediated sensitization to food and environmental allergens. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee.
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
Description from UniProt.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:0110098
MESH:C565293
OMIM:605803
UMLS:C1853965
MONDO:0011596
High level summary of knowledge for a disease, including descriptions and datasource references.