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nut midline carcinoma
Disease Summary
Associated Targets (2)
Tchem
1
Tbio
1
Mondo Description A rare, highly aggressive and lethal carcinoma that affects children and young adults. It arises from midline epithelial structures, most commonly the head, neck, and mediastinum. It is a poorly differentiated carcinoma and is characterized by mutations and rearrangement of the NUT gene. A balanced translocation t(15;19) is present that results in the creation of a fusion gene involving the NUT gene, most commonly BRD4-NUT fusion gene.
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:0060463
EFO:0005783
NCIT:C45716
ONCOTREE:NMCHN
Orphanet:443167
UMLS:C1707291
UMLS:CN237663
MONDO:0005563
High level summary of knowledge for a disease, including descriptions and datasource references.