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leukemia, acute lymphocytic, susceptibility to, 1
Disease Summary
Associated Targets (12)
Tbio
8
Tclin
2
Tchem
2
Uniprot Description A subtype of acute leukemia, a cancer of the white blood cells. ALL is a malignant disease of bone marrow and the most common malignancy diagnosed in children. The malignant cells are lymphoid precursor cells (lymphoblasts) that are arrested in an early stage of development. The lymphoblasts replace the normal marrow elements, resulting in a marked decrease in the production of normal blood cells. Consequently, anemia, thrombocytopenia, and neutropenia occur to varying degrees. The lymphoblasts also proliferate in organs other than the marrow, particularly the liver, spleen, and lymphnodes.
Mondo Term and Equivalent IDs
MONDO:0013108: leukemia, acute lymphocytic, susceptibility to, 1
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Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from UniProt.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
OMIM:613065
UMLS:C2751595
MONDO:0013108
High level summary of knowledge for a disease, including descriptions and datasource references.