Name Development Level Target Family
Sodium/potassium-transporting ATPase subunit alpha-4 Tclin Transporter
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Tclin Ion Channel
Equilibrative nucleoside transporter 1 Tclin Transporter
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Tchem Enzyme
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Tclin Enzyme
Sodium/potassium-transporting ATPase subunit beta-3 Tclin Transporter
Sodium/potassium-transporting ATPase subunit gamma Tclin Enzyme
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Tclin Enzyme
Sodium/potassium-transporting ATPase subunit beta-2 Tclin Transporter
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A Tclin Enzyme
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Tclin Enzyme
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' Tclin Enzyme
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Tclin Enzyme
cGMP-specific 3',5'-cyclic phosphodiesterase Tclin Enzyme
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Tclin Enzyme
Sodium/potassium-transporting ATPase subunit alpha-2 Tclin Transporter
Sodium/potassium-transporting ATPase subunit alpha-3 Tclin Transporter
Guanylate cyclase soluble subunit beta-2 Tclin Enzyme
Angiotensin-converting enzyme Tclin Enzyme
Guanylate cyclase soluble subunit alpha-2 Tclin Enzyme
Neprilysin Tclin Enzyme
Leukotriene A-4 hydrolase Tchem Enzyme
cGMP-dependent 3',5'-cyclic phosphodiesterase Tclin Enzyme
Beta-1 adrenergic receptor Tclin GPCR
Ryanodine receptor 2 Tclin Ion Channel
Mineralocorticoid receptor Tclin Nuclear Receptor
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Tclin Enzyme
cAMP-specific 3',5'-cyclic phosphodiesterase 7B Tclin Enzyme
Sodium/potassium-transporting ATPase subunit alpha-1 Tclin Transporter
Sodium/potassium-transporting ATPase subunit beta-1 Tclin Transporter
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Tclin Enzyme
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Tclin Enzyme
Guanylate cyclase soluble subunit beta-1 Tclin Enzyme
Guanylate cyclase soluble subunit alpha-3 Tclin Enzyme
Solute carrier family 12 member 3 Tclin Transporter
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 Tclin Ion Channel
Beta-2 adrenergic receptor Tclin GPCR
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Tclin Enzyme
cGMP-inhibited 3',5'-cyclic phosphodiesterase B Tclin Enzyme
Protein prune homolog Tchem Non-IDG
Type-1 angiotensin II receptor Tclin GPCR
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A Tclin Enzyme
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Tclin Enzyme
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Tclin Enzyme
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Tclin Ion Channel
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Tclin Enzyme
Name Description
digoxin A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
TCRDv4.6.0
DrugCentral Indication
DrugCentral
digoxin