Name Development Level Target Family
Protein cereblon Tclin Non-IDG
Name Description
thalidomide A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
TCRDv4.6.0
DrugCentral Indication
DrugCentral
thalidomide