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wet macular degeneration

Disease Summary
Associated Targets (179)
Tbio

117

Tchem

31

Tdark

20

Tclin

11


Explore Associated Targets
Mondo Description A form of RETINAL degeneration in which abnormal CHOROIDAL NEOVASCULARIZATION occurs under the RETINA and MACULA LUTEA, causing bleeding and leaking of fluid. This leads to bulging and or lifting of the macula and the distortion or destruction of central vision.
Mondo Term and Equivalent IDs
MONDO:0005417:  wet macular degeneration
DOID:10873: Kuhnt-Junius degeneration
EFO:0004683: 
ICD9:362.52: 
MESH:D057135: 
SCTID:414173003: 
UMLS:C0271084: 
UMLS:C2237660: 
GWAS Targets (293)
Items per page:
1 – 5 of 293
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Complement factor H (CFH)
Tbio
4
9
0
2.4
99.8
Complement factor H-related protein 3 (CFHR3)
Tbio
3
7
0
2.4
99.6
Potassium channel subfamily T member 2 (KCNT2)
Tchem
3
5
0
2.4
99.1
Complement factor B (CFB)
Tchem
3
5
0
1.8
98.7
Histone-lysine N-methyltransferase EHMT2 (EHMT2)
Tchem
3
5
0
1.8
98.7
Items per page:
1 – 5 of 293
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Complement factor H (CFH)
Tbio
0
2.4
99.8
Complement factor H-related protein 3 (CFHR3)
Tbio
0
2.4
99.6
Potassium channel subfamily T member 2 (KCNT2)
Tchem
0
2.4
99.1
Complement factor B (CFB)
Tchem
0
1.8
98.7
Histone-lysine N-methyltransferase EHMT2 (EHMT2)
Tchem
0
1.8
98.7
Target Novelty (Tin-x)