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wet macular degeneration

Disease Summary
Associated Targets (192)
Tbio

126

Tchem

35

Tdark

19

Tclin

12


Explore Associated Targets
Mondo Description A form of RETINAL degeneration in which abnormal CHOROIDAL NEOVASCULARIZATION occurs under the RETINA and MACULA LUTEA, causing bleeding and leaking of fluid. This leads to bulging and or lifting of the macula and the distortion or destruction of central vision.
Mondo Term and Equivalent IDs
MONDO:0005417:  wet macular degeneration
DOID:10873: Kuhnt-Junius degeneration
EFO:0004683: 
ICD9:362.52: 
MESH:D057135: 
SCTID:414173003: 
UMLS:C0271084: 
UMLS:C2237660: 
GWAS Targets (321)
Items per page:
1 – 5 of 321
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Complement factor H (CFH)
Tbio
4
9
0
2.4
99.8
Potassium channel subfamily T member 2 (KCNT2)
Tchem
4
6
0
2.3
99.7
Complement factor H-related protein 3 (CFHR3)
Tbio
3
7
0
2.4
99.6
Age-related maculopathy susceptibility protein 2 (ARMS2)
Tbio
5
3
0
2.3
99.5
Serine protease HTRA1 (HTRA1)
Tchem
5
3
0
2.3
99.5
Items per page:
1 – 5 of 321
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Complement factor H (CFH)
Tbio
0
2.4
99.8
Potassium channel subfamily T member 2 (KCNT2)
Tchem
0
2.3
99.7
Complement factor H-related protein 3 (CFHR3)
Tbio
0
2.4
99.6
Age-related maculopathy susceptibility protein 2 (ARMS2)
Tbio
0
2.3
99.5
Serine protease HTRA1 (HTRA1)
Tchem
0
2.3
99.5
Target Novelty (Tin-x)