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Reactome Pathway
Target Development Level
IDG Target Lists
Data Source
Family
PANTHER Class
DTO Class
Interacting Virus
Interacting Viral Protein (Virus)
JAX/MGI Phenotype
GWAS
UniProt Disease

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Reactome Pathway
Diseases of signal transduction

Targets (387)
Items per page:
1 – 10 of 387
TdarkFAM131BProtein FAM131B
Gene Details
UniProt ID: Q86XD5
Family: 
Knowledge Metrics
PPIs: 119
PubMed Score: 1.03
PubTator Score: 0.71
Antibody Count: 41
Log Novelty: 0.14
Illumination Graph
TdarkOPN1MWMedium-wave-sensitive opsin 1
Gene Details
UniProt ID: P04001
Family: GPCR
Knowledge Metrics
PPIs: 18
PubMed Score: 0.88
PubTator Score: 67.03
Antibody Count: 28
Log Novelty: -0.15
Illumination Graph
TdarkPSMA8Proteasome subunit alpha-type 8
Gene Details
UniProt ID: Q8TAA3
Family: Enzyme
Knowledge Metrics
PPIs: 231
PubMed Score: 0.31
PubTator Score: 0.63
Antibody Count: 64
Log Novelty: -0.15
Illumination Graph
TdarkFAM114A2Protein FAM114A2
Gene Details
UniProt ID: Q9NRY5
Family: 
Knowledge Metrics
PPIs: 104
PubMed Score: 1.4
PubTator Score: 1
Antibody Count: 59
Log Novelty: -0.29
Illumination Graph
TdarkNEURL1BE3 ubiquitin-protein ligase NEURL1B
Gene Details
UniProt ID: A8MQ27
Family: Enzyme
Knowledge Metrics
PPIs: 57
PubMed Score: 2.73
PubTator Score: 1.55
Antibody Count: 41
Log Novelty: -0.75
Illumination Graph
TbioRASAL3RAS protein activator like-3
Gene Details
UniProt ID: Q86YV0
Family: 
Knowledge Metrics
PPIs: 73
PubMed Score: 4.35
PubTator Score: 1.4
Antibody Count: 67
Log Novelty: -1.11
Illumination Graph
TdarkPOLR2DDNA-directed RNA polymerase II subunit RPB4
Gene Details
UniProt ID: O15514
Family: Enzyme
Knowledge Metrics
PPIs: 573
PubMed Score: 3.41
PubTator Score: 1.81
Antibody Count: 174
Log Novelty: -1.27
Illumination Graph
TdarkPSMB3Proteasome subunit beta type-3
Gene Details
UniProt ID: P49720
Family: Enzyme
Knowledge Metrics
PPIs: 334
PubMed Score: 3.01
PubTator Score: 4.35
Antibody Count: 122
Log Novelty: -1.3
Illumination Graph
TbioFGFR1OPFGFR1 oncogene partner
Gene Details
UniProt ID: O95684
Family: 
Knowledge Metrics
PPIs: 197
PubMed Score: 5.92
PubTator Score: 12.76
Antibody Count: 259
Log Novelty: -1.61
Illumination Graph
TbioSPRED3Sprouty-related, EVH1 domain-containing protein 3
Gene Details
UniProt ID: Q2MJR0
Family: 
Knowledge Metrics
PPIs: 85
PubMed Score: 5.35
PubTator Score: 2.81
Antibody Count: 73
Log Novelty: -1.62
Illumination Graph
Items per page:
1 – 10 of 387