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Overlap of Reactome Pathway

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Reactome Pathway
Target Development Level
Data Source
Family
PANTHER Class
DTO Class
Expression: UniProt Tissue
GO Process
GO Component
GO Function
Associated Disease
JAX/MGI Phenotype
GWAS

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Reactome Pathway
Defective HLCS causes multiple carboxylase deficiency

Targets (7)
Items per page:
1 – 7 of 7
TbioMCCC2Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
Gene Details
UniProt ID: Q9HCC0
Family: Enzyme
Knowledge Metrics
PPIs: 86
PubMed Score: 14.39
PubTator Score: 92.86
Antibody Count: 251
Log Novelty: -2.71
Illumination Graph
TchemHLCSBiotin--protein ligase
Gene Details
UniProt ID: P50747
Family: Enzyme
Knowledge Metrics
PPIs: 105
PubMed Score: 69.25
PubTator Score: 325.13
Antibody Count: 141
Log Novelty: -4.14
Illumination Graph
TbioMCCC1Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
Gene Details
UniProt ID: Q96RQ3
Family: Enzyme
Knowledge Metrics
PPIs: 117
PubMed Score: 88.82
PubTator Score: 41.82
Antibody Count: 154
Log Novelty: -4.39
Illumination Graph
TbioPCCBPropionyl-CoA carboxylase beta chain, mitochondrial
Gene Details
UniProt ID: P05166
Family: Enzyme
Knowledge Metrics
PPIs: 107
PubMed Score: 97.41
PubTator Score: 49.3
Antibody Count: 188
Log Novelty: -4.52
Illumination Graph
TbioPCCAPropionyl-CoA carboxylase alpha chain, mitochondrial
Gene Details
UniProt ID: P05165
Family: Enzyme
Knowledge Metrics
PPIs: 97
PubMed Score: 185.9
PubTator Score: 89.01
Antibody Count: 174
Log Novelty: -5.27
Illumination Graph
TbioPCPyruvate carboxylase, mitochondrial
Gene Details
UniProt ID: P11498
Family: Enzyme
Knowledge Metrics
PPIs: 222
PubMed Score: 295.06
PubTator Score: 3944.75
Antibody Count: 325
Log Novelty: -5.91
Illumination Graph
TchemACACAAcetyl-CoA carboxylase 1
Gene Details
UniProt ID: Q13085
Family: Enzyme
Knowledge Metrics
PPIs: 201
PubMed Score: 374.31
PubTator Score: 142.81
Antibody Count: 581
Log Novelty: -6
Illumination Graph
Items per page:
1 – 7 of 7