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Overlap of Reactome Pathway

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Reactome Pathway
Target Development Level
IDG Target Lists
Data Source
Family
PANTHER Class
DTO Class
Expression: UniProt Tissue
GO Process
GO Component
GO Function
Associated Disease
JAX/MGI Phenotype
GWAS

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Reactome Pathway
CD28 dependent PI3K/Akt signaling

Targets (22)
Items per page:
1 – 10 of 22
TchemMAP3K14Mitogen-activated protein kinase kinase kinase 14
Gene Details
UniProt ID: Q99558
Family: Kinase
Knowledge Metrics
PPIs: 174
PubMed Score: 28.06
PubTator Score: 175.27
Antibody Count: 318
Log Novelty: -3.35
Illumination Graph
TbioPRR5Proline-rich protein 5
Gene Details
UniProt ID: P85299
Family: Other
Knowledge Metrics
PPIs: 38
PubMed Score: 15.21
PubTator Score: 1.4
Antibody Count: 169
Log Novelty: -3.42
Illumination Graph
TbioTHEM4Acyl-coenzyme A thioesterase THEM4
Gene Details
UniProt ID: Q5T1C6
Family: Enzyme
Knowledge Metrics
PPIs: 40
PubMed Score: 58.03
PubTator Score: 38.52
Antibody Count: 77
Log Novelty: -3.95
Illumination Graph
TbioPIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma
Gene Details
UniProt ID: Q92569
Family: Enzyme
Knowledge Metrics
PPIs: 392
PubMed Score: 72.97
PubTator Score: 51.81
Antibody Count: 230
Log Novelty: -4.3
Illumination Graph
TbioMAPKAP1Target of rapamycin complex 2 subunit MAPKAP1
Gene Details
UniProt ID: Q9BPZ7
Family: Other
Knowledge Metrics
PPIs: 80
PubMed Score: 71.02
PubTator Score: 597.83
Antibody Count: 294
Log Novelty: -4.34
Illumination Graph
TbioPIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta
Gene Details
UniProt ID: O00459
Family: Enzyme
Knowledge Metrics
PPIs: 472
PubMed Score: 115.32
PubTator Score: 373.97
Antibody Count: 571
Log Novelty: -4.79
Illumination Graph
TbioTRIB3Tribbles homolog 3
Gene Details
UniProt ID: Q96RU7
Family: Kinase
Knowledge Metrics
PPIs: 86
PubMed Score: 151.52
PubTator Score: 180.86
Antibody Count: 525
Log Novelty: -4.79
Illumination Graph
TchemMAP3K8Mitogen-activated protein kinase kinase kinase 8
Gene Details
UniProt ID: P41279
Family: Kinase
Knowledge Metrics
PPIs: 88
PubMed Score: 213.44
PubTator Score: 126.82
Antibody Count: 552
Log Novelty: -5.15
Illumination Graph
TchemPDPK13-phosphoinositide-dependent protein kinase 1
Gene Details
UniProt ID: O15530
Family: Kinase
Knowledge Metrics
PPIs: 180
PubMed Score: 228.31
PubTator Score: 104.05
Antibody Count: 876
Log Novelty: -5.45
Illumination Graph
TbioMLST8Target of rapamycin complex subunit LST8
Gene Details
UniProt ID: Q9BVC4
Family: Other
Knowledge Metrics
PPIs: 177
PubMed Score: 210.88
PubTator Score: 50.59
Antibody Count: 447
Log Novelty: -5.47
Illumination Graph
Items per page:
1 – 10 of 22