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Overlap of Reactome Pathway

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Reactome Pathway
Target Development Level
Data Source
Family
PANTHER Class
DTO Class
Expression: UniProt Tissue
GO Process
GO Component
GO Function
Associated Disease
JAX/MGI Phenotype
GWAS

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Reactome Pathway
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Targets (92)
Items per page:
1 – 10 of 92
TbioPIK3AP1Phosphoinositide 3-kinase adapter protein 1
Gene Details
UniProt ID: Q6ZUJ8
Family: Enzyme
Knowledge Metrics
PPIs: 53
PubMed Score: 7.42
PubTator Score: 16.43
Antibody Count: 305
Log Novelty: -2.16
Illumination Graph
TdarkIGHV3-11Immunoglobulin heavy variable 3-11
Gene Details
UniProt ID: P01762
Family: Other
Knowledge Metrics
PPIs: 152
PubMed Score: 8.26
PubTator Score: 4.27
Antibody Count: 0
Log Novelty: -2.39
Illumination Graph
TbioDAPP1Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
Gene Details
UniProt ID: Q9UN19
Family: Other
Knowledge Metrics
PPIs: 80
PubMed Score: 27.03
PubTator Score: 15.26
Antibody Count: 382
Log Novelty: -2.97
Illumination Graph
TchemORAI2Protein orai-2
Gene Details
UniProt ID: Q96SN7
Family: Other
Knowledge Metrics
PPIs: 45
PubMed Score: 32.75
PubTator Score: 23.67
Antibody Count: 145
Log Novelty: -3.81
Illumination Graph
TchemAHCYL1S-adenosylhomocysteine hydrolase-like protein 1
Gene Details
UniProt ID: O43865
Family: Enzyme
Knowledge Metrics
PPIs: 181
PubMed Score: 48.5
PubTator Score: 28.38
Antibody Count: 167
Log Novelty: -3.83
Illumination Graph
TbioSH3KBP1SH3 domain-containing kinase-binding protein 1
Gene Details
UniProt ID: Q96B97
Family: Enzyme
Knowledge Metrics
PPIs: 279
PubMed Score: 76.29
PubTator Score: 57
Antibody Count: 194
Log Novelty: -4.23
Illumination Graph
TbioITPR2Inositol 1,4,5-trisphosphate receptor type 2
Gene Details
UniProt ID: Q14571
Family: Ion Channel
Knowledge Metrics
PPIs: 179
PubMed Score: 154.03
PubTator Score: 51.57
Antibody Count: 112
Log Novelty: -5.08
Illumination Graph
TclinPIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Gene Details
UniProt ID: O00329
Family: Kinase
Knowledge Metrics
PPIs: 244
PubMed Score: 187.86
PubTator Score: 4417.18
Antibody Count: 517
Log Novelty: -5.16
Illumination Graph
TchemPTPN6Tyrosine-protein phosphatase non-receptor type 6
Gene Details
UniProt ID: P29350
Family: Enzyme
Knowledge Metrics
PPIs: 376
PubMed Score: 230.22
PubTator Score: 472.29
Antibody Count: 912
Log Novelty: -5.23
Illumination Graph
TchemBLKTyrosine-protein kinase Blk
Gene Details
UniProt ID: P51451
Family: Kinase
Knowledge Metrics
PPIs: 210
PubMed Score: 186.95
PubTator Score: 84.24
Antibody Count: 537
Log Novelty: -5.34
Illumination Graph
Items per page:
1 – 10 of 92