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A donut chart showing the marginal counts for the top values for each facet.
A bar chart showing counts for intersecting sets for each facet value. The top 5 facet values and their intersections are shown by default. Edit the facet values for custom plots, and filter the list by clicking the bars or circles.
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A classification of the degree to which proteins are studied or not studied, as evidenced by publications, tool compounds and other features.
See details for MAPK11
Radar plot depicting the variety of knowledge obtained by Pharos for this target.
Primary UniProt accession number
A broad classification of protein families
Number of high confidence protein protein interactions for this target.
Jensen Lab generated fractional counting score for the prevalence of this target in PubMed articles.
A score based on text mining PubMed data.
Number of antibodies for this target listed in antibodypedia.com.
Tin-X metric for the relative scarcity of specific publications for this target.
See details for ATF2
See details for MAPK10
See details for MAPK9
See details for MAPK1
See details for MAPK8
See details for MAPK14
See details for MAPK3
See details for JUN
See details for FOS
See interacting proteins on String-db.org
Download Data for ILKAP
Heirarchical classifications for this protein from different ontologies.
Classes for this protein according to Protein ANalysis THrough Evolutionary Relationships (PANTHER) Classification System.
Explore targets in this PANTHER class
Classes for this protein according to by Drug Target Ontology (DTO).
Explore targets in this DTO class
Gene symbols, accession ids and various other target identifiers. Also contains the illumination graph which highlights the amount of knowledge available. Click the '?' button for more information
Description of the protein which includes the UniProt Function and the NCBI Gene Summary.
Uniprot linked accession values, symbols or commonly used abbreviations associated with this particular target.
Approved gene symbol with link to HUGO Gene Nomenclature Committee.
Ensembl identifier links.
List of abbreviations or acronyms of the full target name.
Radar plot depicting the variety of knowledge obtained by Pharos for a particular target. The more spikes in the plot, the more variety. The longer the length, the higher the quantity of that particular knowledge. Clicking the illumination graph opens an expanded view to explore the plot fuller by seeing plot with annotations of the different radii.
Table representing the top 5 knowledge attributes in the illumination graph. The knowledge value property is on a scale of 0 to 1.
https://unmtid-shinyapps.net/shiny/tiga/?gene=ENSG00000132323
https://genevatool.org/gene_table?gene_name=ILKAP
https://glygen.org/protein/Q9H0C8
https://maayanlab.cloud/archs4/gene/ILKAP
A list of related tools that have content for this sprotein.
Descriptions of the IDG illumination level highlighting the milestones attained in the research of this target.
Jensen Lab generated fractional counting score for the prevalence of this gene in Pubmed articles.
Total count of NCBI Gene Reference Into Function hits for target listed in parenthesis, and summary table with links to publications per PMID with the specific text in article that includes the reported target.
Number of antibodies for this target listed in antibodypedia.com
Number of Gene Ontology (GO) annotations for this target, consisting of the sum of GO Functions and GO Processes.
Ligands associated with a target, listed in ChEMBL, with activity over a cutoff relative to the targetclass.
Approved drugs associated with a target.
Genome-wide association studies (GWAS) find associations between phenotypic traits and genes. Target Illumination GWAS Analytics (TIGA) scores and ranks those traits according to a subset of study parameters.
Explore on Target Illumination GWAS Analytics (TIGA)
Orthologous proteins from other species, from OMA, EggNOG, and Inparanoid.
Biochemical pathways containing the current target.
Pathways and diagrams from Reactome.
Find Targets with an overlapping set of PathwayCommons Pathways
A network of biological classes describing the molecular function, cellular locations, and processes genes may carry out, as defined by the Gene Ontology Consortium.
Find Targets with an overlapping set of GO Functions
Find Targets with an overlapping set of GO Components
Function terms describe molecular activities performed by gene products. Terms may be broad, such as "catalytic activity" or narrow, such as "adenylate cyclase activity".
Component terms describe locations relative to cellular structures in which a gene product performs a function.
List of protein to protein interactions associated with this gene. Interactions are reported from Reactome, BioPlex, and StringDB. StringDB score must be above 0.400 to be shown here. Explore on the String-DB website to see lower likelihood targets.
Opens the Target List with this set of targets
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
BioPlex score representing the probability of the protein protein interaction.
BioPlex score representing the probability that the interaction detected was non-specific.
String-DB score representing the confidence in the protein protein interaction.
Data Sources reporting this protein-protein interaction.
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
Integrin-linked protein kinase
Serine/threonine-protein kinase Chk2
Glycogen synthase kinase-3 beta
Mitogen-activated protein kinase 3
Dual specificity mitogen-activated protein kinase kinase 7
Mitogen-activated protein kinase 1
Protein FAM131A
Protein maelstrom homolog
Statistics about the occurence of this target in literature, extracted via text mining. GeneRIFs,and text-mined publications are also displayed. For more details, click the '?' button.
The Pubmed Score (also sometimes referred to as the Jensen Score) is
derived from text mining a set of Pubmed abstracts.
Timeline of pubtator scores for each available year.
Amino acid sequence, and a detailed sequence structure viewer via the Uniprot Protvista viewer.
Bar chart summarizing the number of times each residue appears in the sequence. The bars represent the actual counts, while the gold lines represent the expected counts given the frequency of the amino acids in all human genes.
Amino acid sequence of the target protein.
The protein sequence aligned with structural and functional annotations, as well as disease variants.
List of targets within Pharos that are related to this target.
Occurrence of this target in up to 10 categories of UniProt keywords.
Find Targets with an overlapping set of UniProt Keywords
Occurrence of this target in up to 10 categories of GWAS Traits.
Find Targets with an overlapping set of GWAS Traits
Occurrence of this target in up to 10 categories of JAX/MGI Phenotypes.
Find Targets with an overlapping set of MGI Phenotypes