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Reactome Pathway
AXIN mutants destabilize the destruction complex, activating WNT signaling

Targets (14)
Items per page:
1 – 10 of 14
TbioPPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Gene Details
UniProt ID:  Q15173
Family:  Enzyme
Knowledge Metrics
PPIs:  282
PubMed Score:  9.21
PubTator Score:  9.53
Antibody Count:  92
Log Novelty:  -2.41
Illumination Graph
TbioPPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
Gene Details
UniProt ID:  Q16537
Family:  Enzyme
Knowledge Metrics
PPIs:  326
PubMed Score:  15.87
PubTator Score:  6.05
Antibody Count:  133
Log Novelty:  -2.82
Illumination Graph
TbioPPP2CBSerine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Gene Details
UniProt ID:  P62714
Family:  Enzyme
Knowledge Metrics
PPIs:  405
PubMed Score:  17.23
PubTator Score:  9.41
Antibody Count:  366
Log Novelty:  -3.03
Illumination Graph
TbioPPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
Gene Details
UniProt ID:  Q14738
Family:  Enzyme
Knowledge Metrics
PPIs:  372
PubMed Score:  24.81
PubTator Score:  5.72
Antibody Count:  320
Log Novelty:  -3.22
Illumination Graph
TbioPPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Gene Details
UniProt ID:  P30154
Family:  Enzyme
Knowledge Metrics
PPIs:  360
PubMed Score:  25.24
PubTator Score:  20.12
Antibody Count:  259
Log Novelty:  -3.23
Illumination Graph
TbioPPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Gene Details
UniProt ID:  Q13362
Family:  Enzyme
Knowledge Metrics
PPIs:  306
PubMed Score:  30.76
PubTator Score:  10.01
Antibody Count:  225
Log Novelty:  -3.4
Illumination Graph
TchemPPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Gene Details
UniProt ID:  Q15172
Family:  Enzyme
Knowledge Metrics
PPIs:  315
PubMed Score:  30.4
PubTator Score:  10.17
Antibody Count:  239
Log Novelty:  -3.48
Illumination Graph
TbioPPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Gene Details
UniProt ID:  P30153
Family:  Enzyme
Knowledge Metrics
PPIs:  703
PubMed Score:  71.73
PubTator Score:  34.82
Antibody Count:  359
Log Novelty:  -4.48
Illumination Graph
TbioAMER1APC membrane recruitment protein 1
Gene Details
UniProt ID:  Q5JTC6
Family:  Other
Knowledge Metrics
PPIs:  143
PubMed Score:  114.08
PubTator Score:  59.83
Antibody Count:  96
Log Novelty:  -4.65
Illumination Graph
TchemCSNK1A1Casein kinase I isoform alpha
Gene Details
UniProt ID:  P48729
Family:  Kinase
Knowledge Metrics
PPIs:  207
PubMed Score:  152.19
PubTator Score:  73.52
Antibody Count:  608
Log Novelty:  -5.06
Illumination Graph
Items per page:
1 – 10 of 14