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Overlap of Reactome Pathway

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Reactome Pathway
Target Development Level
Data Source
Family
PANTHER Class
DTO Class
Expression: UniProt Tissue
GO Process
GO Component
GO Function
Associated Disease
JAX/MGI Phenotype
GWAS

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Reactome Pathway
AKT phosphorylates targets in the nucleus

Targets (10)
Items per page:
1 – 10 of 10
TbioFOXO6Forkhead box protein O6
Gene Details
UniProt ID: A8MYZ6
Family: Transcription Factor
Knowledge Metrics
PPIs: 56
PubMed Score: 36.3
PubTator Score: 14.52
Antibody Count: 49
Log Novelty: -3.81
Illumination Graph
TbioRPS6KB2Ribosomal protein S6 kinase beta-2
Gene Details
UniProt ID: Q9UBS0
Family: Kinase
Knowledge Metrics
PPIs: 97
PubMed Score: 42.33
PubTator Score: 103.1
Antibody Count: 719
Log Novelty: -3.84
Illumination Graph
TbioFOXO4Forkhead box protein O4
Gene Details
UniProt ID: P98177
Family: Transcription Factor
Knowledge Metrics
PPIs: 111
PubMed Score: 164.43
PubTator Score: 83.09
Antibody Count: 891
Log Novelty: -5.21
Illumination Graph
TchemAKT3RAC-gamma serine/threonine-protein kinase
Gene Details
UniProt ID: Q9Y243
Family: Kinase
Knowledge Metrics
PPIs: 255
PubMed Score: 282.22
PubTator Score: 159.24
Antibody Count: 1054
Log Novelty: -5.78
Illumination Graph
TchemAKT2RAC-beta serine/threonine-protein kinase
Gene Details
UniProt ID: P31751
Family: Kinase
Knowledge Metrics
PPIs: 324
PubMed Score: 521.93
PubTator Score: 382.72
Antibody Count: 1474
Log Novelty: -6.39
Illumination Graph
TbioNR4A1Nuclear receptor subfamily 4 group A member 1
Gene Details
UniProt ID: P22736
Family: Nuclear Receptor
Knowledge Metrics
PPIs: 172
PubMed Score: 806.92
PubTator Score: 2495.32
Antibody Count: 656
Log Novelty: -6.5
Illumination Graph
TbioFOXO3Forkhead box protein O3
Gene Details
UniProt ID: O43524
Family: Transcription Factor
Knowledge Metrics
PPIs: 389
PubMed Score: 1490.07
PubTator Score: 848.49
Antibody Count: 1051
Log Novelty: -7.2
Illumination Graph
TbioFOXO1Forkhead box protein O1
Gene Details
UniProt ID: Q12778
Family: Transcription Factor
Knowledge Metrics
PPIs: 405
PubMed Score: 1891.55
PubTator Score: 959.38
Antibody Count: 1900
Log Novelty: -7.44
Illumination Graph
TbioCREB1Cyclic AMP-responsive element-binding protein 1
Gene Details
UniProt ID: P16220
Family: Transcription Factor
Knowledge Metrics
PPIs: 629
PubMed Score: 5347.24
PubTator Score: 2205.89
Antibody Count: 2012
Log Novelty: -8.62
Illumination Graph
TchemAKT1RAC-alpha serine/threonine-protein kinase
Gene Details
UniProt ID: P31749
Family: Kinase
Knowledge Metrics
PPIs: 1761
PubMed Score: 29775.56
PubTator Score: 11900.14
Antibody Count: 4668
Log Novelty: -10.35
Illumination Graph
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