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A classification of the degree to which proteins are studied or not studied, as evidenced by publications, tool compounds and other features.
See details for POLR2J2
Radar plot depicting the variety of knowledge obtained by Pharos for this target.
click for section description and definitions
Primary UniProt accession number
A broad classification of protein families
Number of high confidence protein protein interactions for this target.
Jensen Lab generated fractional counting score for the prevalence of this target in PubMed articles.
A score based on text mining PubMed data.
Number of antibodies for this target listed in antibodypedia.com.
Tin-X metric for the relative scarcity of specific publications for this target.
See details for ZNF862
See details for TCF24
See details for HES2
See details for POLR2J3
See details for NSMCE1
See details for BHMG1
See details for USF3
See details for HPS1
See details for ZMYM1
See interacting proteins on String-db.org
Download Data for THSD7B
Heirarchical classifications for this protein from different ontologies.
Classes for this protein according to Protein ANalysis THrough Evolutionary Relationships (PANTHER) Classification System.
Explore targets in this PANTHER class
Classes for this protein according to by Drug Target Ontology (DTO).
Explore targets in this DTO class
Gene symbols, accession ids and various other target identifiers. Also contains the illumination graph which highlights the amount of knowledge available. Click the '?' button for more information
Uniprot linked accession values, symbols or commonly used abbreviations associated with this particular target.
Approved gene symbol with link to HUGO Gene Nomenclature Committee.
Ensembl identifier links.
List of abbreviations or acronyms of the full target name.
Radar plot depicting the variety of knowledge obtained by Pharos for a particular target. The more spikes in the plot, the more variety. The longer the length, the higher the quantity of that particular knowledge. Clicking the illumination graph opens an expanded view to explore the plot fuller by seeing plot with annotations of the different radii.
Table representing the top 5 knowledge attributes in the illumination graph. The knowledge value property is on a scale of 0 to 1.
https://unmtid-shinyapps.net/shiny/tiga/?gene=ENSG00000144229
https://genevatool.org/gene_table?gene_name=THSD7B
https://glygen.org/protein/Q9C0I4
A list of related tools that have content for this protein.
Descriptions of the IDG illumination level highlighting the milestones attained in the research of this target.
Jensen Lab generated fractional counting score for the prevalence of this gene in Pubmed articles.
Total count of NCBI Gene Reference Into Function hits for target listed in parenthesis, and summary table with links to publications per PMID with the specific text in article that includes the reported target.
Number of antibodies for this target listed in antibodypedia.com
Number of Gene Ontology (GO) annotations for this target, consisting of the sum of GO Functions and GO Processes.
Ligands associated with a target, listed in ChEMBL, with activity over a cutoff relative to the targetclass.
Approved drugs associated with a target.
Genome-wide association studies (GWAS) find associations between phenotypic traits and genes. Target Illumination GWAS Analytics (TIGA) scores and ranks those traits according to a subset of study parameters.
Explore on Target Illumination GWAS Analytics (TIGA)
Orthologous proteins from other species, from OMA, EggNOG, and Inparanoid.
Open Tutorial
List of proteins and ligands sourced from the RCSB PDB database
Biochemical pathways containing the current target.
Pathways and diagrams from Reactome.
Find Targets with an overlapping set of Reactome Pathways
A network of biological classes describing the molecular function, cellular locations, and processes genes may carry out, as defined by the Gene Ontology Consortium.
Find Targets with an overlapping set of GO Components
Component terms describe locations relative to cellular structures in which a gene product performs a function.
List of protein to protein interactions associated with this gene. Interactions are reported from Reactome, BioPlex, and StringDB. StringDB score must be above 0.400 to be shown here. Explore on the String-DB website to see lower likelihood targets.
Opens the Target List with this set of targets
A disintegrin and metalloproteinase with thrombospondin motifs 13
String-DB score representing the confidence in the protein protein interaction.
Data Sources reporting this protein-protein interaction.
Semaphorin-5A
Semaphorin-5B
Spondin-1
A disintegrin and metalloproteinase with thrombospondin motifs 15
Thrombospondin type-1 domain-containing protein 7A
A disintegrin and metalloproteinase with thrombospondin motifs 18
Thrombospondin-2
A disintegrin and metalloproteinase with thrombospondin motifs 5
A disintegrin and metalloproteinase with thrombospondin motifs 8
Statistics about the occurence of this target in literature, extracted via text mining. GeneRIFs,and text-mined publications are also displayed. For more details, click the '?' button.
The Pubmed Score (also sometimes referred to as the Jensen Score) is
derived from text mining a set of Pubmed abstracts.
Timeline of pubtator scores for each available year.
Amino acid sequence, and a detailed sequence structure viewer via the Uniprot Protvista viewer.
Bar chart summarizing the number of times each residue appears in the sequence. The bars represent the actual counts, while the gold lines represent the expected counts given the frequency of the amino acids in all human genes.
Amino acid sequence of the target protein.
The protein sequence aligned with structural and functional annotations, as well as disease variants.
List of targets within Pharos that are related to this target.
Occurrence of this target in up to 10 categories of UniProt keywords.
Find Targets with an overlapping set of UniProt Keywords
Occurrence of this target in up to 10 categories of GWAS Traits.
Find Targets with an overlapping set of GWAS Traits