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Tdark
ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 29   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 29   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (90)
GREM2
Tbio
Novelty:  0.01839564
p_int:  0.999957868
p_ni:  0.000042133
Data Source:  BioPlex
EGFL6
Tbio
Novelty:  0.04347552
p_int:  0.999748589
p_ni:  0.000251411
Score:  0.162
Data Source:  BioPlex,STRINGDB
RPS4X
Tbio
Novelty:  0.01396038
p_int:  0.999659643
p_ni:  0.000340355
p_wrong:  2e-9
Score:  0.207
Data Source:  BioPlex,STRINGDB
ANGPT2
Tbio
Novelty:  0.00116183
p_int:  0.99901623
p_ni:  0.00098377
Score:  0.161
Data Source:  BioPlex,STRINGDB
CCDC130
Tdark
Novelty:  0.34042834
p_int:  0.998838946
p_ni:  0.001161054
Score:  0.177
Data Source:  BioPlex,STRINGDB
CHRDL1
Tbio
Novelty:  0.01748654
p_int:  0.998797992
p_ni:  0.001202005
p_wrong:  3e-9
Data Source:  BioPlex
RBFA
Tbio
Novelty:  0.1061138
p_int:  0.99800343
p_ni:  0.00199657
Data Source:  BioPlex
MRM1
Tbio
Family:  Enzyme
Novelty:  0.08762499
p_int:  0.99794922
p_ni:  0.00205078
Data Source:  BioPlex
GADD45GIP1
Tbio
Novelty:  0.03765684
p_int:  0.996753919
p_ni:  0.003246082
Data Source:  BioPlex
GAST
Tbio
Novelty:  0.00011795
p_int:  0.996653606
p_ni:  0.003346394
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (15)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
10
7
4
1.1
95.5
FEV/FEC ratio
1
1
1
76
mean platelet volume
2
2
2
73.4
platelet count
1
1
1
56.2
waist-hip ratio
1
1
1
52
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
1.1
95.5
FEV/FEC ratio
1
76
mean platelet volume
2
73.4
platelet count
1
56.2
waist-hip ratio
1
52
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger ZZ-type and EF-hand domain containing 1
VGNC:9810
455045
Macaque
zinc finger ZZ-type and EF-hand domain containing 1
721518
Mouse
MGI:2444286
195018
Rat
RGD:1311189
287476
Dog
zinc finger ZZ-type and EF-hand domain containing 1
VGNC:48870
489436
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger ZZ-type and EF-hand domain containing 1
Macaque
zinc finger ZZ-type and EF-hand domain containing 1
Mouse
Rat
Dog
zinc finger ZZ-type and EF-hand domain containing 1
Publication Statistics
PubMed Score 2.88
PubMed score by year
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Related Publications
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PMID
Year
Title