ZW10
Centromere/kinetochore protein zw10 homolog
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 0.99 | ||
interacting protein | 0.98 | ||
tissue sample | 0.81 | ||
disease perturbation | 0.79 | ||
transcription factor binding site profile | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Reactome | Amplification of signal from the kinetochores | ||||
Reactome | COPI-dependent Golgi-to-ER retrograde traffic | ||||
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle Checkpoints | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Amplification of signal from the kinetochores | ||||
COPI-dependent Golgi-to-ER retrograde traffic | ||||
Cell Cycle | ||||
Cell Cycle Checkpoints | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
alcohol consumption measurement | 4 | 4 | 4 | 64.3 | |||||
smoking status measurement | 2 | 1 | 2 | 57.3 | |||||
Age-related nuclear cataract | 1 | 1 | 0 | 6.3 | 40.7 | ||||
self reported educational attainment | 1 | 1 | 1 | 31.4 | |||||
parental longevity | 1 | 1 | 1 | 28.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
alcohol consumption measurement | 4 | 64.3 | |||||
smoking status measurement | 2 | 57.3 | |||||
Age-related nuclear cataract | 0 | 6.3 | 40.7 | ||||
self reported educational attainment | 1 | 31.4 | |||||
parental longevity | 1 | 28.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | zw10 kinetochore protein | VGNC:930 | 451554 | |||||
Macaque | zw10 kinetochore protein | 694436 | ||||||
Mouse | MGI:1349478 | 26951 | ||||||
Rat | RGD:1309197 | 363059 | ||||||
Dog | zw10 kinetochore protein | VGNC:48864 | 479433 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | zw10 kinetochore protein | |||||
Macaque | zw10 kinetochore protein | |||||
Mouse | ||||||
Rat | ||||||
Dog | zw10 kinetochore protein | |||||
PMID | Year | Title |
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