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Tbio
ZSCAN21
Zinc finger and SCAN domain-containing protein 21

Protein Summary
Description
Strong transcriptional activator.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000292450
  • ENSP00000292450
  • ENSG00000166529

Symbol
  • ZFP38
  • ZNF38
  • ZNF38
  • Zipro1
  • NY-REN-21
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
molecular function
0.86
protein domain
0.73
transcription factor binding site profile
0.7
tissue
0.69


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.03   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 361   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.03   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 361   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
GRAP2
Tbio
Novelty:  0.00503901
p_int:  0.999996925
p_ni:  0.000003075
Score:  0.209
Data Source:  BioPlex,STRINGDB
ZBED9
Tdark
Novelty:  0.3335355
p_int:  0.999996868
p_ni:  0.000002831
p_wrong:  3.01e-7
Data Source:  BioPlex
VWCE
Tbio
Novelty:  0.09328341
p_int:  0.999987108
p_ni:  0.000012892
Data Source:  BioPlex
ZSCAN20
Tdark
Family:  TF
Novelty:  0.37441538
p_int:  0.999916073
p_ni:  0.000013163
p_wrong:  0.000070765
Score:  0.653
Data Source:  BioPlex,STRINGDB
ZSCAN30
Tdark
Family:  TF
Novelty:  1.6056338
p_int:  0.999835085
p_ni:  0.000010715
p_wrong:  0.0001542
Score:  0.21
Data Source:  BioPlex,STRINGDB
LRP4
Tbio
Novelty:  0.01336125
p_int:  0.999520831
p_ni:  0.000479169
Data Source:  BioPlex
SART3
Tbio
Novelty:  0.02353492
p_int:  0.999488563
p_ni:  0.000509985
p_wrong:  0.000001452
Data Source:  BioPlex
ZKSCAN5
Tdark
Family:  TF
Novelty:  0.09717066
p_int:  0.999259472
p_ni:  0.000617658
p_wrong:  0.00012287
Data Source:  BioPlex
ZNF232
Tdark
Family:  TF
Novelty:  0.68288358
p_int:  0.999252186
p_ni:  0.000521395
p_wrong:  0.00022642
Score:  0.795
Data Source:  BioPlex,STRINGDB
ZNF397
Tbio
Family:  TF
Novelty:  0.60034816
p_int:  0.999249155
p_ni:  0.000750845
Score:  0.699
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
78.3
FEV/FEC ratio
1
1
1
62.5
body height
1
1
1
62.1
1
1
0
1.3
61
erythrocyte count
1
1
1
52.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
78.3
FEV/FEC ratio
1
62.5
body height
1
62.1
0
1.3
61
erythrocyte count
1
52.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 21
VGNC:4591
463584
Mouse
MGI:99182
22697
Rat
RGD:1309981
304342
Dog
zinc finger and SCAN domain containing 21
VGNC:54101
Horse
zinc finger and SCAN domain containing 21 [Source:HGNC Symbol;Acc:HGNC:13104]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 21
Mouse
Rat
Dog
zinc finger and SCAN domain containing 21
Horse
zinc finger and SCAN domain containing 21 [Source:HGNC Symbol;Acc:HGNC:13104]
Publication Statistics
PubMed Score 6.03
PubMed score by year
PubTator Score 2.44
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title