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Tdark
ZSCAN12
Zinc finger and SCAN domain-containing protein 12

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361028
  • ENSP00000354305
  • ENSG00000158691
  • ENST00000396827
  • ENSP00000380039

Symbol
  • KIAA0426
  • ZNF305
  • ZNF96
  • ZFP96
  • ZNF96
  • ZNF305
  • ZNF29K1
  • dJ29K1.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.91
histone modification site profile
0.69
transcription factor binding site profile
0.62
cellular component
0.53
microRNA
0.46


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.79   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 98   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.79   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 98   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
CPM
Tchem
Family:  Enzyme
Novelty:  0.00520702
p_int:  0.999992867
p_ni:  0.000007116
p_wrong:  1.7e-8
Score:  0.169
Data Source:  BioPlex,STRINGDB
HAL
Tbio
Family:  Enzyme
Novelty:  0.01504631
p_int:  0.999320799
p_ni:  0.000679201
Data Source:  BioPlex
DMKN
Tbio
Novelty:  0.08303199
p_int:  0.999179702
p_ni:  0.000818558
p_wrong:  0.00000174
Score:  0.188
Data Source:  BioPlex,STRINGDB
RNASE7
Tbio
Family:  Enzyme
Novelty:  0.01866347
p_int:  0.997981155
p_ni:  0.00201866
p_wrong:  1.85e-7
Data Source:  BioPlex
SERPINA12
Tbio
Novelty:  0.00549132
p_int:  0.997363788
p_ni:  0.002636212
Data Source:  BioPlex
CTSV
Tchem
Family:  Enzyme
Novelty:  0.00916301
p_int:  0.996438671
p_ni:  0.003561328
p_wrong:  1e-9
Data Source:  BioPlex
PGK2
Tbio
Family:  Kinase
Novelty:  0.00832045
p_int:  0.993945724
p_ni:  0.006054168
p_wrong:  1.08e-7
Data Source:  BioPlex
ME1
Tchem
Novelty:  0.00553719
p_int:  0.989468049
p_ni:  0.010531824
p_wrong:  1.26e-7
Score:  0.161
Data Source:  BioPlex,STRINGDB
CST6
Tbio
Novelty:  0.02811473
p_int:  0.981872728
p_ni:  0.018115941
p_wrong:  0.000011332
Data Source:  BioPlex
ALOX12B
Tbio
Family:  Enzyme
Novelty:  0.02778552
p_int:  0.980878607
p_ni:  0.019121393
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (30)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
4
0
1.2
93.7
wellbeing measurement
3
4
4
89.6
major depressive disorder
2
2
1
8.9
86.6
peak expiratory flow
1
1
1
83.9
2
2
0
5
83.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
93.7
wellbeing measurement
4
89.6
major depressive disorder
1
8.9
86.6
peak expiratory flow
1
83.9
0
5
83.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 12
VGNC:7949
462520
Macaque
zinc finger and SCAN domain containing 12
100424938
Mouse
MGI:1099444
22758
Dog
zinc finger and SCAN domain containing 12 [Source:HGNC Symbol;Acc:HGNC:13172]
Horse
zinc finger and SCAN domain containing 12 [Source:HGNC Symbol;Acc:HGNC:13172]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 12
Macaque
zinc finger and SCAN domain containing 12
Mouse
Dog
zinc finger and SCAN domain containing 12 [Source:HGNC Symbol;Acc:HGNC:13172]
Horse
zinc finger and SCAN domain containing 12 [Source:HGNC Symbol;Acc:HGNC:13172]
Publication Statistics
PubMed Score 2.79
PubMed score by year
PubTator Score 1.30
PubTator score by year
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Related Publications
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PMID
Year
Title