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Tbio
ZRANB2
Zinc finger Ran-binding domain-containing protein 2

Protein Summary
Description
Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000254821
  • ENSP00000254821
  • ENSG00000132485
  • ENST00000370920
  • ENSP00000359958
  • ENST00000611683
  • ENSP00000482026

Symbol
  • ZIS
  • ZNF265
  • ZIS
  • ZIS1
  • ZIS2
  • ZNF265
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.99
interacting protein
0.91
drug perturbation
0.87
transcription factor binding site profile
0.85
small molecule perturbation
0.77


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.59   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 264   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.59   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 264   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0