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Tbio
ZNF804A
Zinc finger protein 804A

Protein Summary
Description
The protein encoded by this gene is a zinc finger binding protein. Polymorphisms in this gene, especially rs1344706, are thought to confer increased susceptibility to schizophrenia, bipolar disorder, and heroin addiciton. [provided by RefSeq, Nov 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302277
  • ENSP00000303252
  • ENSG00000170396

Symbol
  • C2orf10
  • C2orf10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.82
histone modification site profile
0.76
cell type or tissue
0.74
tissue sample
0.67
biological term
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 152.61   (req: < 5)
Gene RIFs: 97   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 152.61   (req: >= 5)
Gene RIFs: 97   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
NRGN
Tbio
Novelty:  0.00352757
Score:  0.737
Data Source:  STRINGDB
CACNA1C
Tclin
Family:  IC
Novelty:  0.00099998
Score:  0.709
Data Source:  STRINGDB
WBP1L
Tdark
Novelty:  0.06161133
Score:  0.7
Data Source:  STRINGDB
VRK2
Tbio
Family:  Kinase
Novelty:  0.03300582
Score:  0.687
Data Source:  STRINGDB
ANK3
Tbio
Novelty:  0.00429246
Score:  0.685
Data Source:  STRINGDB
DISC1
Tbio
Novelty:  0.00183442
Score:  0.672
Data Source:  STRINGDB
DTNBP1
Tbio
Novelty:  0.00341619
Score:  0.655
Data Source:  STRINGDB
NRG1
Tbio
Novelty:  0.00095246
Score:  0.631
Data Source:  STRINGDB
CSMD1
Tbio
Novelty:  0.015271
Score:  0.613
Data Source:  STRINGDB
YAE1
Tbio
Novelty:  0.65114343
Score:  0.612
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
9
6
3
1.1
84.3
self reported educational attainment
2
2
2
47.4
intelligence
1
1
1
46.9
neuroticism measurement
4
2
2
5.8
44.1
age at first sexual intercourse measurement
2
2
2
41.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
1.1
84.3
self reported educational attainment
2
47.4
intelligence
1
46.9
neuroticism measurement
2
5.8
44.1
age at first sexual intercourse measurement
2
41.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 804A
VGNC:3885
470600
Macaque
zinc finger protein 804A
707018
Mouse
MGI:2442949
241514
Rat
RGD:1305239
295695
Dog
zinc finger protein 804A
VGNC:48824
610934
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 804A
Macaque
zinc finger protein 804A
Mouse
Rat
Dog
zinc finger protein 804A
Publication Statistics
PubMed Score 152.61
PubMed score by year
PubTator Score 113.13
PubTator score by year
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Related Publications
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PMID
Year
Title