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Tdark
ZNF777
Zinc finger protein 777

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000247930
  • ENSP00000247930
  • ENSG00000196453

Symbol
  • KIAA1285
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
histone modification site profile
0.68
tissue
0.6
tissue sample
0.6
transcription factor binding site profile
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (63)
KLHL21
Tbio
Novelty:  0.20694121
p_int:  0.999967292
p_ni:  0.000032706
p_wrong:  2e-9
Data Source:  BioPlex
CBY1
Tbio
Novelty:  0.0205109
p_int:  0.999938864
p_ni:  0.000042465
p_wrong:  0.000018671
Data Source:  BioPlex
PRKD1
Tchem
Family:  Kinase
Novelty:  0.00128927
p_int:  0.999929457
p_ni:  0.000070496
p_wrong:  4.6e-8
Data Source:  BioPlex
ZC3HAV1
Tbio
Novelty:  0.01357759
p_int:  0.999833691
p_ni:  0.000166309
Score:  0.307
Data Source:  BioPlex,STRINGDB
SHCBP1
Tbio
Novelty:  0.09160318
p_int:  0.999730528
p_ni:  0.000171488
p_wrong:  0.000097984
Data Source:  BioPlex
ZNF398
Tbio
Family:  TF
Novelty:  0.01578856
p_int:  0.99923214
p_ni:  0.00076786
Score:  0.798
Data Source:  BioPlex,STRINGDB
RBAK
Tbio
Family:  TF
Novelty:  0.12597665
p_int:  0.998868005
p_ni:  0.000964804
p_wrong:  0.000167191
Data Source:  BioPlex
IPP
Tbio
Novelty:  0.12841634
p_int:  0.998437782
p_ni:  0.001534786
p_wrong:  0.000027432
Data Source:  BioPlex
SRBD1
Tbio
Novelty:  0.18931356
p_int:  0.997329053
p_ni:  0.002670947
Data Source:  BioPlex
ERP44
Tbio
Novelty:  0.02352693
p_int:  0.996731676
p_ni:  0.0032683
p_wrong:  2.4e-8
Score:  0.255
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diastolic blood pressure
2
1
2
30.9
1
1
0
1.2
8.8
monocyte count
1
1
1
7.6
type 2 diabetes mellitus
1
1
1
0.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diastolic blood pressure
2
30.9
0
1.2
8.8
monocyte count
1
7.6
type 2 diabetes mellitus
1
0.2
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 777
VGNC:4583
463827
Macaque
zinc finger protein 777
711987
Mouse
MGI:1919556
72306
Rat
RGD:1566056
502764
Dog
zinc finger protein 777
VGNC:48814
482786
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 777
Macaque
zinc finger protein 777
Mouse
Rat
Dog
zinc finger protein 777
Publication Statistics
PubMed Score 1.33
PubMed score by year
PubTator Score 0.33
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title