Protein Summary
May be involved in transcriptional regulation.
- ENST00000252797
- ENSP00000252797
- ENSG00000169951
- ENST00000395091
- ENSP00000378526
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.99 | ||
cell type or tissue | 0.61 | ||
histone modification site profile | 0.61 | ||
protein domain | 0.58 | ||
transcription factor binding site profile | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.11 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 103 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.11 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 103 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (39)
SUFU
Novelty: 0.00475249
p_int: 0.999999616
p_ni: 3.83e-7
Score: 0.28
Data Source: BioPlex,STRINGDB
VWCE
Novelty: 0.09328341
p_int: 0.999998336
p_ni: 0.000001487
p_wrong: 1.77e-7
Data Source: BioPlex
SH3PXD2B
Novelty: 0.04207866
p_int: 0.999996907
p_ni: 0.000003093
Score: 0.225
Data Source: BioPlex,STRINGDB
TRIM39
Family: Enzyme
Novelty: 0.0837441
p_int: 0.999995477
p_ni: 0.000004523
Score: 0.154
Data Source: BioPlex,STRINGDB
GTF3C4
Family: Epigenetic
Novelty: 0.28198123
p_int: 0.999994652
p_ni: 0.00000534
p_wrong: 8e-9
Data Source: BioPlex
USP34
Family: Enzyme
Novelty: 0.16444192
p_int: 0.999931352
p_ni: 0.000068648
Score: 0.198
Data Source: BioPlex,STRINGDB
GNE
Family: Enzyme
Novelty: 0.00285751
p_int: 0.999767485
p_ni: 0.0002325
p_wrong: 1.6e-8
Score: 0.161
Data Source: BioPlex,STRINGDB
SMARCAD1
Novelty: 0.04117162
p_int: 0.99952187
p_ni: 0.000478073
p_wrong: 5.7e-8
Data Source: BioPlex
Nearest Tclin Targets
Pathways (4)
Reactome (3)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
RNA Polymerase II Transcription | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (3)
Components (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (15)
Items per page:
1 – 5 of 15
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
lymphocyte count | 3 | 3 | 4 | 96.9 | |||||
myeloid white cell count | 2 | 2 | 2 | 94.8 | |||||
leukocyte count | 2 | 2 | 2 | 90 | |||||
lymphocyte percentage of leukocytes | 2 | 2 | 2 | 85.7 | |||||
neutrophil count | 2 | 2 | 2 | 82.3 | |||||
Items per page:
1 – 5 of 15
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
lymphocyte count | 4 | 96.9 | |||||
myeloid white cell count | 2 | 94.8 | |||||
leukocyte count | 2 | 90 | |||||
lymphocyte percentage of leukocytes | 2 | 85.7 | |||||
neutrophil count | 2 | 82.3 | |||||
Find similar targets by:
IDG Resources
Orthologs (4)
1 – 4 of 4
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:2443581 | 269997 | ||||||
Mouse | MGI:1926171 | 78921 | ||||||
Rat | RGD:7731019 | 102553962 | ||||||
Horse | zinc finger protein 764 | 102149734 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Mouse | ||||||
Rat | ||||||
Horse | zinc finger protein 764 | |||||
Publication Statistics
PubMed Score 2.11
PubMed score by year
PubTator Score 1.00
PubTator score by year
Related Publications
Text Mined References (5)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
---|