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Tbio
ZNF740
Zinc finger protein 740

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000416904
  • ENSP00000409463
  • ENSG00000139651

Symbol
  • TB7
  • Zfp740
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.78
transcription factor perturbation
0.74
transcription factor
0.64
tissue sample
0.61
interacting protein
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.14   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.14   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.904
Data Source:  STRINGDB
TBRG1
Tbio
Novelty:  0.02003439
Score:  0.707
Data Source:  STRINGDB
SPRYD3
Tdark
Novelty:  3.99875244
Score:  0.704
Data Source:  STRINGDB
PDE6B
Tclin
Family:  Enzyme
Novelty:  0.001105
Score:  0.69
Data Source:  STRINGDB
IFNG
Tclin
Novelty:  0.00009731
Score:  0.68
Data Source:  STRINGDB
PDE7A
Tclin
Family:  Enzyme
Novelty:  0.00872596
Score:  0.667
Data Source:  STRINGDB
DNAJC5B
Tdark
Novelty:  0.28962584
Score:  0.65
Data Source:  STRINGDB
REEP5
Tbio
Novelty:  0.00160455
Score:  0.64
Data Source:  STRINGDB
CREB5
Tbio
Family:  TF
Novelty:  0.03857106
Score:  0.63
Data Source:  STRINGDB
PFDN5
Tbio
Novelty:  0.07673574
Score:  0.61
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

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Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
spine bone mineral density
1
1
1
57.8
self reported educational attainment
2
2
2
57.1
mathematical ability
2
2
2
45.6
intelligence
1
1
1
44.2
1
1
1
44.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
spine bone mineral density
1
57.8
self reported educational attainment
2
57.1
mathematical ability
2
45.6
intelligence
1
44.2
1
44.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 740
VGNC:13502
451933
Macaque
zinc finger protein 740
701428
Mouse
MGI:1915994
68744
Rat
RGD:1589052
685834
Dog
zinc finger protein 740
VGNC:48809
486509
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 740
Macaque
zinc finger protein 740
Mouse
Rat
Dog
zinc finger protein 740
Publication Statistics
PubMed Score 94.14
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title