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Tdark
ZNF654
Zinc finger protein 654

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309495
  • ENSP00000312141
  • ENSG00000175105
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.72
kinase perturbation
0.66
tissue sample
0.57
microRNA
0.55
cell line
0.49


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (13)
C3orf38
Tdark
Novelty:  2.10467478
Score:  0.942
Data Source:  STRINGDB
ZNF764
Tdark
Family:  TF
Novelty:  0.76308829
Score:  0.679
Data Source:  STRINGDB
CGGBP1
Tbio
Novelty:  0.10880271
Score:  0.654
Data Source:  STRINGDB
LTN1
Tbio
Family:  Enzyme
Novelty:  0.02604262
Score:  0.639
Data Source:  STRINGDB
NRIP1
Tbio
Novelty:  0.00551568
Score:  0.623
Data Source:  STRINGDB
HDAC1
Tclin
Family:  Epigenetic
Novelty:  0.00065244
Score:  0.609
Data Source:  STRINGDB
ZNF217
Tbio
Family:  TF
Novelty:  0.01313576
Score:  0.573
Data Source:  STRINGDB
ZNF366
Tbio
Family:  TF
Novelty:  0.1166487
Score:  0.561
Data Source:  STRINGDB
PPFIA4
Tbio
Novelty:  0.34141709
Score:  0.53
Data Source:  STRINGDB
KDM5B
Tchem
Family:  TF; Epigenetic
Novelty:  0.00610414
Score:  0.496
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (17)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
3
3
83.3
mean corpuscular hemoglobin concentration
1
1
1
77
comparative body size at age 10, self-reported
1
1
1
63.4
red blood cell density measurement
1
1
1
60.5
body mass index
1
1
1
50.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
83.3
mean corpuscular hemoglobin concentration
1
77
comparative body size at age 10, self-reported
1
63.4
red blood cell density measurement
1
60.5
body mass index
1
50.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1919270
72020
Cow
zinc finger protein 654
100335242
Opossum
zinc finger protein 654
100030564
Xenopus
zinc finger protein 654
XB-GENE-948833
779560
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Cow
zinc finger protein 654
Opossum
zinc finger protein 654
Xenopus
zinc finger protein 654
Publication Statistics
PubMed Score 0.27
PubMed score by year
PubTator Score 0.08
PubTator score by year
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Related Publications
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PMID
Year
Title