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Tbio
ZNF644
Zinc finger protein 644

Protein Summary
Description
May be involved in transcriptional regulation. The protein encoded by this gene is a zinc finger transcription factor that may play a role in eye development. Defects in this gene have been associated with high myopia. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000337393
  • ENSP00000337008
  • ENSG00000122482
  • ENST00000347275
  • ENSP00000340828
  • ENST00000361321
  • ENSP00000354659
  • ENST00000370440
  • ENSP00000359469

Symbol
  • KIAA1221
  • ZEP2
  • NatF
  • MYP21
  • ZEP-2
  • BM-005
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
virus perturbation
0.9
kinase perturbation
0.76
transcription factor binding site profile
0.75
transcription factor
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 33   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 33   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0