Tbio ZNF622 Zinc finger protein 622

Protein Summary

Description

May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development.

Uniprot Accession IDs

• Q969S3

Gene Name

• ZNF622

Ensembl ID

• ENST00000308683
• ENSP00000310042
• ENSG00000173545

Symbol

• ZPR9
• ZPR9

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.96
histone modification site profile	0.83
cellular component	0.74
transcription factor binding site profile	0.74
transcription factor perturbation	0.74

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Zinc Finger Protein 622

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Zinc Finger Protein 622

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.7   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 158   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.7   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 158   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

tutorial

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (3)

GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

Go To Tool

ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

Go To Tool

Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (180)

Explore Interacting Targets

1 – 10 of 180

• See Interactions on String-DB

RPL23A

Tbio

Novelty:  0.02951947

p_int:  0.999970305

p_ni:  0.000029695

p_wrong:  1e-9

Score:  0.553

Data Source:  BioPlex,STRINGDB

CCDC102B

Tdark

Novelty:  0.28075569

p_int:  0.999924858

p_ni:  0.000075107

p_wrong:  3.4e-8

Score:  0.181

Data Source:  BioPlex,STRINGDB

EZR

Tbio

Novelty:  0.00115353

p_int:  0.999784924

p_ni:  0.000203892

p_wrong:  0.000011185

Data Source:  BioPlex

YAF2

Tbio

Novelty:  0.10772286

p_int:  0.999715637

p_ni:  0.000255319

p_wrong:  0.000029044

Score:  0.181

Data Source:  BioPlex,STRINGDB

CAVIN1

Tbio

Family:  Enzyme

Novelty:  0.00780634

p_int:  0.999362567

p_ni:  0.000130849

p_wrong:  0.000506584

Score:  0.189

Data Source:  BioPlex,STRINGDB

PRPF31

Tbio

Novelty:  0.0105753

p_int:  0.999040574

p_ni:  0.000202964

p_wrong:  0.000756462

Score:  0.25

Data Source:  BioPlex,STRINGDB

MELK

Tchem

Family:  Kinase

Novelty:  0.00762154

Score:  0.987

Data Source:  STRINGDB

NMD3

Tbio

Novelty:  0.03505289

Score:  0.983

Data Source:  STRINGDB

EIF6

Tbio

Novelty:  0.01271382

Score:  0.977

Data Source:  STRINGDB

NSA2

Tbio

Novelty:  0.04542275

Score:  0.931

Data Source:  STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (15)

Functions (3)

Components (6)

Processes (6)

Find Similar Targets

Items per page:

10

1 – 3 of 3

GO Term	Evidence	Assigned by
RNA binding	Inferred from High Throughput Direct Assay (HDA)	UniProtKB
DNA-binding transcription factor activity, RNA polymerase II-specific	Non-traceable Author Statement (NAS)	NTNU_SB
zinc ion binding	Inferred from Electronic Annotation (IEA)	InterPro

Disease Associations (null)

No disease associations found

GWAS Traits (0)

No GWAS traits found

Find similar targets by:

UniProt Keyword Find Similar Targets

No Header	No Header
Acetylation
Complete proteome
Cytoplasm
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Repeat
Zinc
Zinc-finger

IDG Resources

No IDG generated resources found

Orthologs (14)

1 – 5 of 14

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 622	VGNC:4238	461736
Mouse	zinc finger protein 622	MGI:1289282	52521
Dog	zinc finger protein 622	VGNC:48777	479383
Horse	zinc finger protein 622	VGNC:25361	100069990
Cow	zinc finger protein 622	VGNC:37315	513617

Species	Name	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 622
Mouse	zinc finger protein 622
Dog	zinc finger protein 622
Horse	zinc finger protein 622
Cow	zinc finger protein 622

Publication Statistics

PubMed Score 6.70

PubMed score by year

Reset Zoom

PubTator Score 2.42

PubTator score by year

Reset Zoom

Related Publications

Text Mined References (11)

GeneRif Annotations (3)

Items per page:

10

0 of 0

PMID	Year	Title