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Tbio
ZNF622
Zinc finger protein 622

Protein Summary
Description
May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000308683
  • ENSP00000310042
  • ENSG00000173545

Symbol
  • ZPR9
  • ZPR9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.96
histone modification site profile
0.83
cellular component
0.74
transcription factor binding site profile
0.74
transcription factor perturbation
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.7   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 158   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.7   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 158   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (180)
RPL23A
Tbio
Novelty:  0.02951947
p_int:  0.999970305
p_ni:  0.000029695
p_wrong:  1e-9
Score:  0.553
Data Source:  BioPlex,STRINGDB
CCDC102B
Tdark
Novelty:  0.28075569
p_int:  0.999924858
p_ni:  0.000075107
p_wrong:  3.4e-8
Score:  0.181
Data Source:  BioPlex,STRINGDB
EZR
Tbio
Novelty:  0.00115353
p_int:  0.999784924
p_ni:  0.000203892
p_wrong:  0.000011185
Data Source:  BioPlex
YAF2
Tbio
Novelty:  0.10772286
p_int:  0.999715637
p_ni:  0.000255319
p_wrong:  0.000029044
Score:  0.181
Data Source:  BioPlex,STRINGDB
CAVIN1
Tbio
Family:  Enzyme
Novelty:  0.00780634
p_int:  0.999362567
p_ni:  0.000130849
p_wrong:  0.000506584
Score:  0.189
Data Source:  BioPlex,STRINGDB
PRPF31
Tbio
Novelty:  0.0105753
p_int:  0.999040574
p_ni:  0.000202964
p_wrong:  0.000756462
Score:  0.25
Data Source:  BioPlex,STRINGDB
MELK
Tchem
Family:  Kinase
Novelty:  0.00762154
Score:  0.987
Data Source:  STRINGDB
NMD3
Tbio
Novelty:  0.03505289
Score:  0.983
Data Source:  STRINGDB
EIF6
Tbio
Novelty:  0.01271382
Score:  0.977
Data Source:  STRINGDB
NSA2
Tbio
Novelty:  0.04542275
Score:  0.931
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 622
VGNC:4238
461736
Mouse
MGI:1289282
52521
Dog
zinc finger protein 622
VGNC:48777
479383
Horse
zinc finger protein 622
VGNC:25361
100069990
Cow
zinc finger protein 622
VGNC:37315
513617
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 622
Mouse
Dog
zinc finger protein 622
Horse
zinc finger protein 622
Cow
zinc finger protein 622
Publication Statistics
PubMed Score 6.70
PubMed score by year
PubTator Score 2.42
PubTator score by year
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Related Publications
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PMID
Year
Title