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Tbio
ZNF592
Zinc finger protein 592

Protein Summary
Description
May be involved in transcriptional regulation. This gene is thought to play a role in a complex developmental pathway and the regulation of genes involved in cerebellar development. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia. [provided by RefSeq, Jan 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299927
  • ENSP00000299927
  • ENSG00000166716
  • ENST00000560079
  • ENSP00000452877

Symbol
  • KIAA0211
  • CAMOS
  • SCAR5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
transcription factor binding site profile
0.75
histone modification site profile
0.74
virus perturbation
0.68
tissue sample
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.29   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 111   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.29   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 111   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (65)
CSNK2B
Tbio
Family:  Kinase
Novelty:  0.00152367
p_int:  0.999995253
p_ni:  0.000004746
p_wrong:  2e-9
Score:  0.185
Data Source:  BioPlex,STRINGDB
GATAD2A
Tbio
Novelty:  0.05599551
p_int:  0.999994453
p_ni:  0.000005547
Score:  0.591
Data Source:  BioPlex,STRINGDB
CSNK2A2
Tchem
Family:  Kinase
Novelty:  0.00231447
p_int:  0.999991211
p_ni:  0.000008788
p_wrong:  1e-9
Score:  0.266
Data Source:  BioPlex,STRINGDB
LLGL2
Tbio
Novelty:  0.07084531
p_int:  0.999946464
p_ni:  0.00005352
p_wrong:  1.6e-8
Score:  0.196
Data Source:  BioPlex,STRINGDB
P4HA3
Tbio
Family:  Enzyme
Novelty:  0.03832564
p_int:  0.999673022
p_ni:  0.000326868
p_wrong:  1.1e-7
Score:  0.16
Data Source:  BioPlex,STRINGDB
ZNF408
Tbio
Family:  TF
Novelty:  0.10649477
p_int:  0.944410522
p_ni:  0.000951259
p_wrong:  0.054638219
Data Source:  BioPlex
INTS6
Tbio
Novelty:  0.02680242
Score:  0.993
Data Source:  STRINGDB
INTS5
Tbio
Novelty:  0.02127142
Score:  0.993
Data Source:  STRINGDB
INTS3
Tbio
Novelty:  0.13398603
Score:  0.993
Data Source:  STRINGDB
ZMYND8
Tbio
Family:  Epigenetic
Novelty:  0.05352096
Score:  0.887
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (17)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
2
6
6
86.2
4
3
1
1.1
59.7
BMI-adjusted waist circumference
1
1
1
54.4
Left ventricular mass to end-diastolic volume ratio
1
1
1
53.3
P wave terminal force measurement
1
2
0
85.5
51.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
6
86.2
1
1.1
59.7
BMI-adjusted waist circumference
1
54.4
Left ventricular mass to end-diastolic volume ratio
1
53.3
P wave terminal force measurement
0
85.5
51.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 592
VGNC:13460
453608
Macaque
zinc finger protein 592
695601
Mouse
MGI:2443541
233410
Rat
RGD:1308705
293038
Dog
zinc finger protein 592
VGNC:48769
488751
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 592
Macaque
zinc finger protein 592
Mouse
Rat
Dog
zinc finger protein 592
Publication Statistics
PubMed Score 8.29
PubMed score by year
PubTator Score 5.42
PubTator score by year
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Related Publications
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PMID
Year
Title