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Tdark
ZNF579
Zinc finger protein 579

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000325421
  • ENSP00000320188
  • ENSG00000218891
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
transcription factor binding site profile
0.65
tissue sample
0.63
cell line
0.6
transcription factor
0.47


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.1   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.1   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
CHCHD10
Tbio
Novelty:  0.01659548
p_int:  0.999999786
p_ni:  2.13e-7
Data Source:  BioPlex
TNFRSF13B
Tbio
Novelty:  0.00338954
p_int:  0.999999464
p_ni:  5.36e-7
Data Source:  BioPlex
CHCHD2
Tbio
Novelty:  0.01615338
p_int:  0.999997229
p_ni:  0.00000277
Data Source:  BioPlex
PRM2
Tbio
Novelty:  0.0050028
p_int:  0.999956812
p_ni:  0.000043187
p_wrong:  1e-9
Data Source:  BioPlex
DDX54
Tbio
Family:  Enzyme
Novelty:  0.12769464
p_int:  0.999766447
p_ni:  0.000233553
Data Source:  BioPlex
ZNF385C
Tdark
Novelty:  2.23931637
p_int:  0.999698614
p_ni:  0.000301386
Data Source:  BioPlex
P4HA3
Tbio
Family:  Enzyme
Novelty:  0.03832564
p_int:  0.9996331
p_ni:  0.0003669
Data Source:  BioPlex
ASNA1
Tbio
Family:  Enzyme
Novelty:  0.01260233
p_int:  0.998877026
p_ni:  0.001122972
p_wrong:  2e-9
Score:  0.199
Data Source:  BioPlex,STRINGDB
DDX50
Tbio
Family:  Enzyme
Novelty:  0.05314506
p_int:  0.998539053
p_ni:  0.001460947
Data Source:  BioPlex
LBR
Tbio
Family:  Epigenetic
Novelty:  0.00205961
p_int:  0.998281653
p_ni:  0.001718344
p_wrong:  3e-9
Score:  0.683
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
3
1
3
80.4
triglyceride measurement
3
2
3
72.7
insomnia measurement
1
2
0
1.1
56.3
BMI-adjusted hip circumference
1
1
1
42.3
BMI-adjusted waist-hip ratio
2
1
2
34.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
3
80.4
triglyceride measurement
3
72.7
insomnia measurement
0
1.1
56.3
BMI-adjusted hip circumference
1
42.3
BMI-adjusted waist-hip ratio
2
34.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 579
VGNC:11509
737054
Macaque
zinc finger protein 579
106992421
Mouse
MGI:1915740
68490
Rat
RGD:1308475
308339
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 579
Macaque
zinc finger protein 579
Mouse
Rat
Publication Statistics
PubMed Score 0.10
PubMed score by year
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Related Publications
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PMID
Year
Title