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Tdark
ZNF576
Zinc finger protein 576

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336564
  • ENSP00000337852
  • ENSG00000124444
  • ENST00000391965
  • ENSP00000375827
  • ENST00000525771
  • ENSP00000436182
  • ENST00000528387
  • ENSP00000435934
  • ENST00000529930
  • ENSP00000435463
  • ENST00000533118
  • ENSP00000435899
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.77
cell type or tissue
0.66
tissue
0.62
protein domain
0.58
cell line
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.06   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.06   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (14)
POGZ
Tbio
Novelty:  0.03603188
p_int:  0.999999726
p_ni:  2.74e-7
Score:  0.194
Data Source:  BioPlex,STRINGDB
ZNF618
Tdark
Novelty:  0.43589506
p_int:  0.999981953
p_ni:  0.000018026
p_wrong:  2.1e-8
Score:  0.243
Data Source:  BioPlex,STRINGDB
AJUBA
Tbio
Novelty:  0.03561829
p_int:  0.9999799
p_ni:  0.000020092
p_wrong:  8e-9
Score:  0.218
Data Source:  BioPlex,STRINGDB
ZBTB40
Tbio
Family:  TF
Novelty:  0.17413605
p_int:  0.999946599
p_ni:  0.000043838
p_wrong:  0.000009563
Score:  0.228
Data Source:  BioPlex,STRINGDB
ZBED1
Tbio
Family:  TF
Novelty:  0.01645222
p_int:  0.999878556
p_ni:  0.000121444
Score:  0.198
Data Source:  BioPlex,STRINGDB
ZBTB10
Tbio
Family:  TF
Novelty:  0.05707286
p_int:  0.999868275
p_ni:  0.000131725
Score:  0.546
Data Source:  BioPlex,STRINGDB
LIMD1
Tbio
Novelty:  0.04868333
p_int:  0.999177807
p_ni:  0.000821747
p_wrong:  4.46e-7
Score:  0.33
Data Source:  BioPlex,STRINGDB
RBBP6
Tbio
Family:  Enzyme
Novelty:  0.03147368
p_int:  0.998724476
p_ni:  0.001275524
Score:  0.185
Data Source:  BioPlex,STRINGDB
PDLIM7
Tbio
Novelty:  0.00544518
p_int:  0.989268555
p_ni:  0.010731443
p_wrong:  2e-9
Score:  0.645
Data Source:  BioPlex,STRINGDB
ZBTB33
Tbio
Family:  TF
Novelty:  0.01327474
p_int:  0.984064519
p_ni:  0.015935481
Score:  0.163
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (30)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urokinase plasminogen activator surface receptor measurement
2
4
4
99.2
TNF-related apoptosis-inducing ligand measurement
2
1
2
89.9
neutrophil count
4
1
4
78.3
myeloid white cell count
2
1
2
78.2
leukocyte count
3
1
3
77.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urokinase plasminogen activator surface receptor measurement
4
99.2
TNF-related apoptosis-inducing ligand measurement
2
89.9
neutrophil count
4
78.3
myeloid white cell count
2
78.2
leukocyte count
3
77.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Horse
zinc finger protein 576
VGNC:25348
100070243
Cow
zinc finger protein 576
VGNC:37305
616814
Species
Name
OMA
EggNOG
Inparanoid
Horse
zinc finger protein 576
Cow
zinc finger protein 576
Publication Statistics
PubMed Score 0.06
PubMed score by year
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Related Publications
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PMID
Year
Title