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Tdark
ZNF574
Zinc finger protein 574

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359044
  • ENSP00000351939
  • ENSG00000105732
  • ENST00000600245
  • ENSP00000469029

Symbol
  • FP972
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.71
kinase perturbation
0.71
transcription factor binding site profile
0.69
cell type or tissue
0.64
tissue
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 54   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 54   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (61)
SHCBP1
Tbio
Novelty:  0.09160318
p_int:  0.999995311
p_ni:  0.000004688
p_wrong:  1e-9
Data Source:  BioPlex
THAP12
Tbio
Family:  TF
Novelty:  0.21092098
p_int:  0.99999163
p_ni:  0.000008371
Score:  0.708
Data Source:  BioPlex,STRINGDB
TRIM41
Tbio
Family:  Enzyme
Novelty:  0.17238173
p_int:  0.99994752
p_ni:  0.00005248
Score:  0.158
Data Source:  BioPlex,STRINGDB
ANKRD28
Tbio
Family:  Enzyme
Novelty:  0.10895759
p_int:  0.999786524
p_ni:  0.000213476
Score:  0.196
Data Source:  BioPlex,STRINGDB
IFFO1
Tdark
Novelty:  0.38051741
p_int:  0.999396365
p_ni:  0.000603597
p_wrong:  3.8e-8
Data Source:  BioPlex
PPP6R2
Tbio
Family:  Enzyme
Novelty:  0.12886225
p_int:  0.997983349
p_ni:  0.002016651
Data Source:  BioPlex
XAGE1A
Tbio
Novelty:  0.04421526
p_int:  0.988853502
p_ni:  0.011146498
Data Source:  BioPlex
ZC3HAV1
Tbio
Novelty:  0.01357759
p_int:  0.959877303
p_ni:  0.040122697
Data Source:  BioPlex
RPS16
Tbio
Novelty:  0.00261983
p_int:  0.945378811
p_ni:  0.054621182
p_wrong:  7e-9
Data Source:  BioPlex
RPS2
Tbio
Novelty:  0.00412313
p_int:  0.937489588
p_ni:  0.062510412
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
2
1
2
64
lymphocyte count
2
1
2
53.3
low density lipoprotein cholesterol measurement
1
1
1
50.6
alcohol consumption measurement
2
2
2
45.6
alkaline phosphatase measurement
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
2
64
lymphocyte count
2
53.3
low density lipoprotein cholesterol measurement
1
50.6
alcohol consumption measurement
2
45.6
alkaline phosphatase measurement
1
42.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 574
VGNC:11512
456069
Macaque
zinc finger protein 574
706729
Mouse
MGI:2442951
232976
Rat
RGD:1311420
308434
Dog
zinc finger protein 574
VGNC:48762
484479
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 574
Macaque
zinc finger protein 574
Mouse
Rat
Dog
zinc finger protein 574
Publication Statistics
PubMed Score 0.27
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
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PMID
Year
Title