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Tdark
ZNF558
Zinc finger protein 558

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301475
  • ENSP00000301475
  • ENSG00000167785
  • ENST00000601372
  • ENSP00000471277
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.64
protein domain
0.58
microRNA
0.51
cell line
0.5
tissue
0.46


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.84   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 97   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.84   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 97   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (22)
APOA1
Tbio
Novelty:  0.0001216
p_int:  0.999627071
p_ni:  0.000372898
p_wrong:  3.1e-8
Score:  0.261
Data Source:  BioPlex,STRINGDB
SERPINA1
Tbio
Novelty:  0.00014098
p_int:  0.990115269
p_ni:  0.009884687
p_wrong:  4.4e-8
Score:  0.236
Data Source:  BioPlex,STRINGDB
RCBTB2
Tbio
Novelty:  0.04244536
p_int:  0.944975306
p_ni:  0.034361337
p_wrong:  0.020663358
Score:  0.52
Data Source:  BioPlex,STRINGDB
FTL
Tbio
Novelty:  0.00235168
p_int:  0.822749059
p_ni:  0.177246919
p_wrong:  0.000004022
Score:  0.195
Data Source:  BioPlex,STRINGDB
ALB
Tchem
Novelty:  0.00000616
p_int:  0.763966469
p_ni:  0.236033531
Score:  0.261
Data Source:  BioPlex,STRINGDB
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.903
Data Source:  STRINGDB
OR2Z1
Tdark
Family:  oGPCR
Novelty:  1.80952381
Score:  0.699
Data Source:  STRINGDB
TRIM61
Tdark
Novelty:  0.46482206
Score:  0.605
Data Source:  STRINGDB
ZZZ3
Tdark
Family:  TF
Novelty:  0.23862921
Score:  0.542
Data Source:  STRINGDB
UBL4B
Tdark
Novelty:  0.56877836
Score:  0.541
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cancer antigen 125 measurement
1
1
1
68.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cancer antigen 125 measurement
1
68.6
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1921681
72230
Horse
zinc finger protein 558
100064134
Pig
zinc finger protein 558
100514703
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Horse
zinc finger protein 558
Pig
zinc finger protein 558
Publication Statistics
PubMed Score 1.84
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title