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Tdark
ZNF554
Zinc finger protein 554

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000317243
  • ENSP00000321132
  • ENSG00000172006
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.79
tissue sample
0.65
protein domain
0.58
cell line
0.53
histone modification site profile
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (11)
SAV1
Tbio
Novelty:  0.00962335
p_int:  0.999982276
p_ni:  0.000017724
Data Source:  BioPlex
ZNF808
Tdark
Family:  TF
Novelty:  0.83652177
p_int:  0.999969917
p_ni:  2e-9
p_wrong:  0.00003008
Data Source:  BioPlex
TRIM37
Tbio
Family:  Enzyme
Novelty:  0.02515451
p_int:  0.998894369
p_ni:  0.000812141
p_wrong:  0.000293489
Data Source:  BioPlex
STK3
Tchem
Family:  Kinase
Novelty:  0.0529257
p_int:  0.997876146
p_ni:  0.002123854
Data Source:  BioPlex
STK4
Tchem
Family:  Kinase
Novelty:  0.02104423
p_int:  0.994363622
p_ni:  0.005636378
Data Source:  BioPlex
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.989176876
p_ni:  0.010823124
Score:  0.947
Data Source:  BioPlex,STRINGDB
MYADM
Tbio
Novelty:  0.11475375
Score:  0.567
Data Source:  STRINGDB
ZNF474
Tdark
Novelty:  1.18085106
Score:  0.511
Data Source:  STRINGDB
HMCES
Tbio
Family:  Enzyme
Novelty:  0.01229889
Score:  0.44
Data Source:  STRINGDB
SETDB1
Tbio
Family:  TF; Epigenetic
Novelty:  0.00609294
Score:  0.43
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
6
3
6
97.4
testosterone measurement
4
4
4
91.8
1
1
0
25
78.6
1
1
0
50
76.5
low density lipoprotein cholesterol measurement
3
3
3
64.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
6
97.4
testosterone measurement
4
91.8
0
25
78.6
0
50
76.5
low density lipoprotein cholesterol measurement
3
64.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 554
VGNC:2147
744575
Macaque
zinc finger protein 554
711821
Dog
zinc finger protein 554
VGNC:48759
100686725
Horse
zinc finger protein 554
VGNC:25341
100060272
Cow
zinc finger protein 554
VGNC:37301
100125579
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 554
Macaque
zinc finger protein 554
Dog
zinc finger protein 554
Horse
zinc finger protein 554
Cow
zinc finger protein 554
Publication Statistics
PubMed Score 1.20
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title