Protein Summary
May be involved in transcriptional regulation.
- ENST00000317243
- ENSP00000321132
- ENSG00000172006
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.79 | ||
tissue sample | 0.65 | ||
protein domain | 0.58 | ||
cell line | 0.53 | ||
histone modification site profile | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.2 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 128 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.2 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 128 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (11)
ZNF808
Family: TF
Novelty: 0.83652177
p_int: 0.999969917
p_ni: 2e-9
p_wrong: 0.00003008
Data Source: BioPlex
TRIM37
Family: Enzyme
Novelty: 0.02515451
p_int: 0.998894369
p_ni: 0.000812141
p_wrong: 0.000293489
Data Source: BioPlex
STK3
Family: Kinase
Novelty: 0.0529257
p_int: 0.997876146
p_ni: 0.002123854
Data Source: BioPlex
STK4
Family: Kinase
Novelty: 0.02104423
p_int: 0.994363622
p_ni: 0.005636378
Data Source: BioPlex
TRIM28
Family: Epigenetic
Novelty: 0.00778381
p_int: 0.989176876
p_ni: 0.010823124
Score: 0.947
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (4)
Reactome (3)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
RNA Polymerase II Transcription | ||||
Viral Interactions (0)
Gene Ontology Terms (5)
Functions (3)
Components (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations (null)
GWAS Traits (9)
Items per page:
1 – 5 of 9
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 6 | 3 | 6 | 97.4 | |||||
testosterone measurement | 4 | 4 | 4 | 91.8 | |||||
1 | 1 | 0 | 25 | 78.6 | |||||
1 | 1 | 0 | 50 | 76.5 | |||||
low density lipoprotein cholesterol measurement | 3 | 3 | 3 | 64.3 | |||||
Items per page:
1 – 5 of 9
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 6 | 97.4 | |||||
testosterone measurement | 4 | 91.8 | |||||
0 | 25 | 78.6 | |||||
0 | 50 | 76.5 | |||||
low density lipoprotein cholesterol measurement | 3 | 64.3 | |||||
Find similar targets by:
IDG Resources
Orthologs (5)
1 – 5 of 5
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | zinc finger protein 554 | VGNC:2147 | 744575 | |||||
Macaque | zinc finger protein 554 | 711821 | ||||||
Dog | zinc finger protein 554 | VGNC:48759 | 100686725 | |||||
Horse | zinc finger protein 554 | VGNC:25341 | 100060272 | |||||
Cow | zinc finger protein 554 | VGNC:37301 | 100125579 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | zinc finger protein 554 | |||||
Macaque | zinc finger protein 554 | |||||
Dog | zinc finger protein 554 | |||||
Horse | zinc finger protein 554 | |||||
Cow | zinc finger protein 554 | |||||
Publication Statistics
PubMed Score 1.20
PubMed score by year
PubTator Score 0.25
PubTator score by year
Related Publications
Text Mined References (5)
Items per page:
0 of 0
PMID | Year | Title |
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