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Tdark
ZNF550
Zinc finger protein 550

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000325134
  • ENSP00000446224
  • ENSG00000251369
  • ENST00000376230
  • ENSP00000469537
  • ENST00000447310
  • ENSP00000469580
  • ENST00000457177
  • ENSP00000469679
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
cell type or tissue
0.58
protein domain
0.58
tissue
0.57
cell line
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.07   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 123   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.07   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
MEIOC
Tdark
Novelty:  0.85732988
p_int:  0.999999956
p_ni:  4e-8
p_wrong:  4e-9
Score:  0.189
Data Source:  BioPlex,STRINGDB
ZNF714
Tdark
Family:  TF
Novelty:  0.73743398
p_int:  0.999998097
p_ni:  7.77e-7
p_wrong:  0.000001126
Score:  0.187
Data Source:  BioPlex,STRINGDB
YTHDC2
Tbio
Family:  Enzyme
Novelty:  0.05211009
p_int:  0.999968415
p_ni:  0.000031585
Score:  0.151
Data Source:  BioPlex,STRINGDB
TRIM37
Tbio
Family:  Enzyme
Novelty:  0.02515451
p_int:  0.998923964
p_ni:  0.001059484
p_wrong:  0.000016552
Score:  0.169
Data Source:  BioPlex,STRINGDB
ZNF460
Tdark
Family:  TF
Novelty:  0.71547663
p_int:  0.998316161
p_ni:  0.001683174
p_wrong:  6.65e-7
Data Source:  BioPlex
ZNF92
Tbio
Family:  TF
Novelty:  0.05724663
p_int:  0.997249948
p_ni:  0.002750052
Data Source:  BioPlex
RBAK
Tbio
Family:  TF
Novelty:  0.12597665
p_int:  0.997109058
p_ni:  0.002889476
p_wrong:  0.000001466
Data Source:  BioPlex
USP34
Tbio
Family:  Enzyme
Novelty:  0.16444192
p_int:  0.997054463
p_ni:  0.002945529
p_wrong:  8e-9
Score:  0.198
Data Source:  BioPlex,STRINGDB
TRIM41
Tbio
Family:  Enzyme
Novelty:  0.17238173
p_int:  0.995862118
p_ni:  0.004137758
p_wrong:  1.23e-7
Score:  0.158
Data Source:  BioPlex,STRINGDB
FBLN5
Tbio
Novelty:  0.00599598
p_int:  0.994504495
p_ni:  0.004422383
p_wrong:  0.001073123
Score:  0.191
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
3
4
90.6
mean reticulocyte volume
1
1
1
62.1
balding measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
90.6
mean reticulocyte volume
1
62.1
balding measurement
1
24.5
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 550
VGNC:11468
456330
Macaque
zinc finger protein 550
106994887
Dog
zinc finger protein 550
VGNC:48758
102155260
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 550
Macaque
zinc finger protein 550
Dog
zinc finger protein 550
Publication Statistics
PubMed Score 0.07
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title