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Tdark
ZNF517
Zinc finger protein 517

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359971
  • ENSP00000353058
  • ENSG00000197363
  • ENST00000531720
  • ENSP00000436103
  • ENST00000533965
  • ENSP00000435166
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.6
protein domain
0.58
cell line
0.52
microRNA
0.5
tissue
0.46


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.44   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.44   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
NUDT12
Tbio
Family:  Enzyme
Novelty:  0.18740719
p_int:  0.999993989
p_ni:  0.000005972
p_wrong:  3.9e-8
Score:  0.217
Data Source:  BioPlex,STRINGDB
NPHP3
Tbio
Novelty:  0.02857926
p_int:  0.999911451
p_ni:  0.000088549
Data Source:  BioPlex
MICAL1
Tbio
Family:  Enzyme
Novelty:  0.02668048
p_int:  0.999887061
p_ni:  0.000112937
p_wrong:  1e-9
Data Source:  BioPlex
LRP1B
Tbio
Novelty:  0.01443405
p_int:  0.998503838
p_ni:  0.001496162
Data Source:  BioPlex
NDUFAF7
Tbio
Family:  Enzyme
Novelty:  0.24691414
p_int:  0.997209221
p_ni:  0.002790696
p_wrong:  8.2e-8
Data Source:  BioPlex
IPP
Tbio
Novelty:  0.12841634
p_int:  0.995563242
p_ni:  0.004314624
p_wrong:  0.000122134
Score:  0.188
Data Source:  BioPlex,STRINGDB
ERBIN
Tbio
Novelty:  0.01419561
p_int:  0.987252521
p_ni:  0.012747479
Data Source:  BioPlex
SORL1
Tbio
Novelty:  0.00380895
p_int:  0.986923288
p_ni:  0.013076712
Data Source:  BioPlex
PPP2R5E
Tbio
Family:  Enzyme
Novelty:  0.05974697
p_int:  0.986025183
p_ni:  0.013974817
Score:  0.174
Data Source:  BioPlex,STRINGDB
PPP2CA
Tchem
Family:  Enzyme
Novelty:  0.00496839
p_int:  0.977158535
p_ni:  0.022841465
Score:  0.174
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum alanine aminotransferase measurement
1
1
0
10.3
76.8
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum alanine aminotransferase measurement
0
10.3
76.8
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 517
VGNC:14620
747726
Macaque
zinc finger protein 517
704360
Dog
zinc finger protein 517
VGNC:48747
102153851
Horse
zinc finger protein 517 [Source:HGNC Symbol;Acc:HGNC:27984]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 517
Macaque
zinc finger protein 517
Dog
zinc finger protein 517
Horse
zinc finger protein 517 [Source:HGNC Symbol;Acc:HGNC:27984]
Publication Statistics
PubMed Score 0.44
PubMed score by year
PubTator Score 0.83
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title