Tdark ZNF514 Zinc finger protein 514

Protein Summary

Description

May be involved in transcriptional regulation.

Uniprot Accession IDs

• Q96K75
• Q5JPJ3

Gene Name

• ZNF514

Ensembl ID

• ENST00000295208
• ENSP00000295208
• ENSG00000144026
• ENST00000411425
• ENSP00000405509

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.58
tissue sample	0.54
tissue	0.52
cell line	0.49
histone modification site profile	0.47

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.09   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 107   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.09   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

tutorial

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (3)

GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

Go To Tool

ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

Go To Tool

Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (36)

Explore Interacting Targets

1 – 10 of 36

• See Interactions on String-DB

ZNF430

Tdark

Family:  TF

Novelty:  3.98895047

p_int:  0.999409817

p_ni:  0.000581569

p_wrong:  0.000008614

Data Source:  BioPlex

SMARCAD1

Tbio

Novelty:  0.04117162

p_int:  0.999306716

p_ni:  0.000693283

Data Source:  BioPlex

SIRT1

Tchem

Family:  Epigenetic

Novelty:  0.00022265

p_int:  0.998747015

p_ni:  0.001252985

Data Source:  BioPlex

USP34

Tbio

Family:  Enzyme

Novelty:  0.16444192

p_int:  0.980200151

p_ni:  0.019799665

p_wrong:  1.83e-7

Data Source:  BioPlex

TRIM28

Tbio

Family:  Epigenetic

Novelty:  0.00778381

p_int:  0.959035834

p_ni:  0.040964166

Score:  0.903

Data Source:  BioPlex,STRINGDB

CENPB

Tbio

Novelty:  0.0036225

p_int:  0.953451821

p_ni:  0.046546972

p_wrong:  0.000001207

Data Source:  BioPlex

ZNF92

Tbio

Family:  TF

Novelty:  0.05724663

p_int:  0.926385163

p_ni:  0.071515801

p_wrong:  0.002099036

Data Source:  BioPlex

PCBP3

Tbio

Novelty:  0.11681812

p_int:  0.8968134

p_ni:  0.103057737

p_wrong:  0.000128863

Data Source:  BioPlex

MRPS5

Tbio

Novelty:  0.11423336

Score:  0.568

Data Source:  STRINGDB

FAHD2B

Tdark

Family:  Enzyme

Novelty:  1.47557507

Score:  0.562

Data Source:  STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (4)

Reactome (3)

KEGG (1)

Gene expression (Transcription) (R-HSA-74160)

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Find Similar Targets

Items per page:

5

1 – 3 of 3

Data Source	Name	Explore in Pharos	Explore in Source
Reactome	Gene expression (Transcription)	1452 targets	R-HSA-74160
Reactome	Generic Transcription Pathway	1195 targets	R-HSA-212436
Reactome	RNA Polymerase II Transcription	1314 targets	R-HSA-73857

Name	Explore in Pharos	Explore in Source
Gene expression (Transcription)	1452 targets	R-HSA-74160
Generic Transcription Pathway	1195 targets	R-HSA-212436
RNA Polymerase II Transcription	1314 targets	R-HSA-73857

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (4)

Functions (3)

Components (1)

Find Similar Targets

Items per page:

10

1 – 3 of 3

GO Term	Evidence	Assigned by
DNA-binding transcription factor activity, RNA polymerase II-specific	Inferred from Sequence Alignment (ISA)	NTNU_SB
DNA binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW
metal ion binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW

Disease Associations (null)

No disease associations found

GWAS Traits (0)

No GWAS traits found

Find similar targets by:

UniProt Keyword Find Similar Targets

No Header	No Header
Complete proteome
DNA-binding
Metal-binding
Nucleus
Reference proteome
Repeat
Transcription
Transcription regulation
Zinc
Zinc-finger

IDG Resources

No IDG generated resources found

Orthologs (5)

1 – 5 of 5

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 514	VGNC:10810	470431
Macaque	zinc finger protein 514		705392
Dog	zinc finger protein 514		611670
Horse	zinc finger protein 514	VGNC:25336	102149683
Cow	zinc finger protein 514	VGNC:37293	782049

Species	Name	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 514
Macaque	zinc finger protein 514
Dog	zinc finger protein 514
Horse	zinc finger protein 514
Cow	zinc finger protein 514

Publication Statistics

PubMed Score 0.09

PubMed score by year

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Related Publications

Text Mined References (5)

Items per page:

10

0 of 0

PMID	Year	Title