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Tbio
ZNF512
Zinc finger protein 512

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein containing four putative zinc finger motifs. Zinc finger motifs may bind to proteins or nucleic acids. Zinc finger-containing proteins are involved in a variety of processes, including regulation of transcription. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Sep 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355467
  • ENSP00000347648
  • ENSG00000243943
  • ENST00000413371
  • ENSP00000395660
  • ENST00000416005
  • ENSP00000407038
  • ENST00000556601
  • ENSP00000451572

Symbol
  • KIAA1805
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.83
histone modification site profile
0.77
transcription factor binding site profile
0.74
kinase perturbation
0.66
cell line
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.96   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.96   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (106)
ZNF273
Tdark
Family:  TF
Novelty:  2.21830681
p_int:  0.999965797
p_ni:  0.000034202
p_wrong:  1e-9
Data Source:  BioPlex
ZNF724
Tdark
Family:  TF
Novelty:  21.16304348
p_int:  0.999882789
p_ni:  0.000117202
p_wrong:  9e-9
Data Source:  BioPlex
RPL26L1
Tdark
Novelty:  0.75408617
p_int:  0.999063739
p_ni:  0.000936261
Data Source:  BioPlex
WDR3
Tbio
Novelty:  0.15410886
p_int:  0.99665661
p_ni:  0.002756575
p_wrong:  0.000586815
Data Source:  BioPlex
ZNF346
Tbio
Novelty:  0.00204191
p_int:  0.979693278
p_ni:  0.020304404
p_wrong:  0.000002318
Data Source:  BioPlex
BLM
Tchem
Novelty:  0.00662454
p_int:  0.978273267
p_ni:  0.021726733
Score:  0.153
Data Source:  BioPlex,STRINGDB
DDX31
Tbio
Family:  Enzyme
Novelty:  2.84646195
p_int:  0.970258179
p_ni:  0.029741821
Score:  0.179
Data Source:  BioPlex,STRINGDB
RPL30
Tbio
Novelty:  0.0134194
p_int:  0.970122499
p_ni:  0.029877501
Score:  0.315
Data Source:  BioPlex,STRINGDB
NEPRO
Tbio
Novelty:  0.12980261
p_int:  0.969918135
p_ni:  0.030081459
p_wrong:  4.06e-7
Score:  0.177
Data Source:  BioPlex,STRINGDB
NAT10
Tbio
Family:  Enzyme
Novelty:  0.02453679
p_int:  0.965122196
p_ni:  0.034877804
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (183)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
71
20
94
7.3
100
C-reactive protein measurement
12
8
19
99.8
total cholesterol measurement
28
10
35
3
99.6
urate measurement
8
4
9
5.2
99.5
low density lipoprotein cholesterol measurement
48
6
50
99.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
94
7.3
100
C-reactive protein measurement
19
99.8
total cholesterol measurement
35
3
99.6
urate measurement
9
5.2
99.5
low density lipoprotein cholesterol measurement
50
99.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 512
VGNC:474
741878
Macaque
zinc finger protein 512
702324
Mouse
MGI:1917345
269639
Rat
RGD:1561526
313906
Dog
zinc finger protein 512
608296
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 512
Macaque
zinc finger protein 512
Mouse
Rat
Dog
zinc finger protein 512
Publication Statistics
PubMed Score 3.96
PubMed score by year
PubTator Score 0.04
PubTator score by year
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Related Publications
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PMID
Year
Title