Pharos : Target Details

Tdark

Protein Summary

Description

May be involved in transcriptional regulation.

Uniprot Accession IDs

Gene Name

ZNF511

Ensembl ID

ENST00000359035
ENSP00000351929
ENSG00000198546
ENST00000361518
ENSP00000355251

Illumination Graph

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.75

tissue sample	0.68

tissue	0.6

cell type or tissue	0.52

transcription factor binding site profile	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85 (req: < 5)

View Publications

Gene RIFs: 0 (req: <= 3)

Antibodies: 64 (req: <= 50)

View Antibodies

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85 (req: >= 5)

Gene RIFs: 0 (req: > 3)

Antibodies: 64 (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

View GO Terms

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (4)

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

View Data

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GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

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ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

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Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (31)

Explore Interacting Targets

1 – 10 of 31

See Interactions on String-DB

LSM5

Tbio

Novelty: 0.12669584

p_int: 0.999999668

p_ni: 1.2e-8

p_wrong: 3.19e-7

Score: 0.485

Data Source: BioPlex,STRINGDB

LSM7

Tbio

Novelty: 0.09112723

p_int: 0.99997252

p_ni: 8.73e-7

p_wrong: 0.000026607

Data Source: BioPlex

LSM3

Tbio

Novelty: 0.05044984

p_int: 0.999706321

p_ni: 0.000051052

p_wrong: 0.000242626

Data Source: BioPlex

XAGE1A

Tbio

Novelty: 0.04421526

p_int: 0.999679091

p_ni: 0.000272252

p_wrong: 0.000048657

Data Source: BioPlex

WASF1

Tbio

Novelty: 0.00977488

p_int: 0.999128004

p_ni: 0.000871952

p_wrong: 4.4e-8

Score: 0.527

Data Source: BioPlex,STRINGDB

WASF2

Tbio

Novelty: 0.00968798

p_int: 0.998218538

p_ni: 0.001781462

Score: 0.416

Data Source: BioPlex,STRINGDB

ABI2

Tbio

Novelty: 0.02324355

p_int: 0.997261016

p_ni: 0.002738984

Score: 0.771

Data Source: BioPlex,STRINGDB

KLHL15

Tbio

Novelty: 0.54712519

p_int: 0.996946707

p_ni: 0.003053293

Data Source: BioPlex

LSM6

Tbio

Novelty: 0.09507671

p_int: 0.996566736

p_ni: 0.00000139

p_wrong: 0.003431874

Data Source: BioPlex

TMCO6

Tdark

Novelty: 4.07407407

p_int: 0.995302955

p_ni: 5.5e-8

p_wrong: 0.004696991

Score: 0.694

Data Source: BioPlex,STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (4)

Functions (3)

Components (1)

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Items per page:

1 – 3 of 3

GO Term	Evidence	Assigned by
DNA-binding transcription factor activity, RNA polymerase II-specific	Inferred from Sequence Alignment (ISA)	NTNU_SB

DNA binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW

metal ion binding	Inferred from Electronic Annotation (IEA)	UniProtKB-KW

Disease Associations (null)

No disease associations found

GWAS Traits (4)

Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

1 – 4 of 4

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)
urinary metabolite measurement	EFO_0005116	1	1	1		67.3

blood metabolite measurement	EFO_0005664	1	1	1		57.8

longevity	EFO_0004300	1	1	0	3.5	40.7

testosterone measurement	EFO_0004908	1	1	1		28.1

Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

1 – 4 of 4

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)
urinary metabolite measurement	EFO_0005116	1		67.3

blood metabolite measurement	EFO_0005664	1		57.8

longevity	EFO_0004300	0	3.5	40.7

testosterone measurement	EFO_0004908	1		28.1

Beta Count

Odds Ratio

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UniProt Keyword

Find Similar Targets

No Header	No Header
Alternative splicing

Complete proteome

DNA-binding

Metal-binding

Methylation

Nucleus

Reference proteome

Repeat

Transcription

Transcription regulation

GWAS Trait

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IDG Resources

No IDG generated resources found

Orthologs (10)

1 – 5 of 10

Species	Name	Source ID	Gene ID
Chimp	zinc finger protein 511	VGNC:12563	739595

Macaque	ZNF511-PRAP1 readthrough [Source:HGNC Symbol;Acc:HGNC:38088]

Mouse	zinc finger protein 511	MGI:1917002	69752

Rat	zinc finger protein 511	RGD:1308585	293586

Dog	zinc finger protein 511		608198

Species	Name	OMA	EggNOG	Inparanoid
Chimp	zinc finger protein 511

Macaque	ZNF511-PRAP1 readthrough [Source:HGNC Symbol;Acc:HGNC:38088]

Mouse	zinc finger protein 511

Rat	zinc finger protein 511

Dog	zinc finger protein 511

Publication Statistics

PubMed Score 0.85

PubMed score by year

PubTator Score 0.92

PubTator score by year

Related Publications

Text Mined References (6)

Items per page:

0 of 0

PMID	Year	Title