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Tdark
ZNF491
Zinc finger protein 491

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000323169
  • ENSP00000313443
  • ENSG00000177599
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.82
histone modification site profile
0.7
cell line
0.58
tissue
0.53
cell type or tissue
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.15   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 41   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.15   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (17)
BPIFA2
Tbio
Novelty:  0.01533858
p_int:  0.999984291
p_ni:  0.000015653
p_wrong:  5.6e-8
Score:  0.188
Data Source:  BioPlex,STRINGDB
IGHA2
Tbio
p_int:  0.999955661
p_ni:  0.000043943
p_wrong:  3.95e-7
Data Source:  BioPlex
MUC7
Tbio
Novelty:  0.00750654
p_int:  0.999871982
p_ni:  0.000047766
p_wrong:  0.000080252
Score:  0.188
Data Source:  BioPlex,STRINGDB
CST2
Tbio
Novelty:  0.02114441
p_int:  0.999759023
p_ni:  0.000240589
p_wrong:  3.89e-7
Score:  0.165
Data Source:  BioPlex,STRINGDB
JCHAIN
Tbio
Novelty:  0.00172454
p_int:  0.997020564
p_ni:  0.000957674
p_wrong:  0.002021762
Score:  0.181
Data Source:  BioPlex,STRINGDB
PIGR
Tbio
Novelty:  0.0025812
p_int:  0.995785599
p_ni:  0.004214362
p_wrong:  3.9e-8
Score:  0.175
Data Source:  BioPlex,STRINGDB
CST4
Tbio
Novelty:  0.00773554
p_int:  0.994953011
p_ni:  0.005046962
p_wrong:  2.8e-8
Data Source:  BioPlex
ZG16B
Tbio
Novelty:  0.08792924
p_int:  0.991443403
p_ni:  0.00855653
p_wrong:  6.7e-8
Data Source:  BioPlex
IGHA1
Tbio
p_int:  0.989086747
p_ni:  0.010913252
p_wrong:  1e-9
Data Source:  BioPlex
HIST2H2AB
Tbio
Novelty:  0.06772132
p_int:  0.972788213
p_ni:  0.027195226
p_wrong:  0.000016562
Score:  0.17
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
1
1
1
50.6
1
1
1
45.2
vitamin D measurement
2
2
2
43.8
4
1
1
1.2
35
self reported educational attainment
1
1
1
29
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
1
50.6
1
45.2
vitamin D measurement
2
43.8
1
1.2
35
self reported educational attainment
1
29
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.15
PubMed score by year
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Related Publications
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PMID
Year
Title