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Tdark
ZNF483
Zinc finger protein 483

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309235
  • ENSP00000311679
  • ENSG00000173258
  • ENST00000358151
  • ENSP00000350871

Symbol
  • KIAA1962
  • ZKSCAN16
  • ZSCAN48
  • ZKSCAN16
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
histone modification site profile
0.64
microRNA
0.58
disease
0.48
cell line
0.45


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.8   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.8   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
ZYG11A
Tbio
Novelty:  0.13413639
p_int:  0.999990549
p_ni:  0.000009451
Score:  0.163
Data Source:  BioPlex,STRINGDB
TRIM24
Tchem
Family:  Epigenetic
Novelty:  0.00532747
p_int:  0.999964524
p_ni:  0.000035476
Score:  0.165
Data Source:  BioPlex,STRINGDB
ZKSCAN3
Tbio
Family:  TF
Novelty:  0.06833314
p_int:  0.999917743
p_ni:  0.000082257
Score:  0.728
Data Source:  BioPlex,STRINGDB
ZKSCAN4
Tbio
Family:  TF
Novelty:  0.33154485
p_int:  0.999861715
p_ni:  0.000138278
p_wrong:  7e-9
Score:  0.82
Data Source:  BioPlex,STRINGDB
ZNF174
Tbio
Family:  TF
Novelty:  0.05970272
p_int:  0.999805601
p_ni:  0.000194399
Score:  0.686
Data Source:  BioPlex,STRINGDB
ZNF197
Tdark
Family:  TF
Novelty:  0.30062428
p_int:  0.999779997
p_ni:  0.000147288
p_wrong:  0.000072715
Score:  0.638
Data Source:  BioPlex,STRINGDB
VTN
Tbio
Family:  TF
Novelty:  0.00046861
p_int:  0.999342814
p_ni:  0.000657177
p_wrong:  9e-9
Data Source:  BioPlex
SCAND1
Tbio
Novelty:  0.06863895
p_int:  0.999294229
p_ni:  0.000705754
p_wrong:  1.7e-8
Score:  0.747
Data Source:  BioPlex,STRINGDB
ZKSCAN1
Tbio
Family:  TF
Novelty:  0.08190662
p_int:  0.997417081
p_ni:  0.002582918
p_wrong:  1e-9
Score:  0.652
Data Source:  BioPlex,STRINGDB
ZNF446
Tdark
Family:  TF
Novelty:  0.80369039
p_int:  0.996335509
p_ni:  0.003664489
p_wrong:  2e-9
Score:  0.795
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menarche
4
4
2
2.6
90.8
puberty onset measurement
2
2
3
76.6
body height
1
1
1
72.9
reticulocyte measurement
1
1
1
35
apolipoprotein A 1 measurement
1
1
1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menarche
2
2.6
90.8
puberty onset measurement
3
76.6
body height
1
72.9
reticulocyte measurement
1
35
apolipoprotein A 1 measurement
1
33.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 483
VGNC:4908
473018
Macaque
zinc finger protein 483
708612
Mouse
MGI:3510405
100041581
Rat
RGD:727958
170955
Dog
zinc finger protein 483
VGNC:48737
481664
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 483
Macaque
zinc finger protein 483
Mouse
Rat
Dog
zinc finger protein 483
Publication Statistics
PubMed Score 1.80
PubMed score by year
PubTator Score 1.04
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title