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Tdark
ZNF416
Zinc finger protein 416

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000196489
  • ENSP00000196489
  • ENSG00000083817
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
cell line
0.64
histone modification site profile
0.61
protein domain
0.58
tissue
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.1   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 90   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.1   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 90   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (15)
PGK2
Tbio
Family:  Kinase
Novelty:  0.00832045
p_int:  0.998807192
p_ni:  0.001192777
p_wrong:  3e-8
Score:  0.18
Data Source:  BioPlex,STRINGDB
TRIM39
Tbio
Family:  Enzyme
Novelty:  0.0837441
p_int:  0.998473512
p_ni:  0.001526488
Score:  0.201
Data Source:  BioPlex,STRINGDB
TUBA3C
Tchem
Novelty:  0.0187396
p_int:  0.995805425
p_ni:  0.004194575
Score:  0.15
Data Source:  BioPlex,STRINGDB
TRIM37
Tbio
Family:  Enzyme
Novelty:  0.02515451
p_int:  0.944394394
p_ni:  0.008096518
p_wrong:  0.047509087
Score:  0.776
Data Source:  BioPlex,STRINGDB
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.865317346
p_ni:  0.134682654
Score:  0.914
Data Source:  BioPlex,STRINGDB
CENPB
Tbio
Novelty:  0.0036225
p_int:  0.822037292
p_ni:  0.177962708
Score:  0.204
Data Source:  BioPlex,STRINGDB
ZNF211
Tdark
Family:  TF
Novelty:  1.09151646
p_int:  0.813591902
p_ni:  0.000005985
p_wrong:  0.186402112
Score:  0.83
Data Source:  BioPlex,STRINGDB
PUS7L
Tdark
Family:  Enzyme
Novelty:  0.96856727
Score:  0.631
Data Source:  STRINGDB
NWD1
Tdark
Novelty:  0.28220226
Score:  0.602
Data Source:  STRINGDB
MAGEE2
Tdark
Novelty:  0.67122204
Score:  0.58
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
3
4
90.6
mean reticulocyte volume
1
1
1
62.1
balding measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
90.6
mean reticulocyte volume
1
62.1
balding measurement
1
24.5
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 416
VGNC:2176
469042
Macaque
zinc finger protein 416
708399
Rat
RGD:1311663
292548
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 416
Macaque
zinc finger protein 416
Rat
Publication Statistics
PubMed Score 1.10
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title