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Tbio
ZNF410
Zinc finger protein 410

Protein Summary
Description
Transcription factor that activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324593
  • ENSP00000323293
  • ENSG00000119725
  • ENST00000398139
  • ENSP00000381208
  • ENST00000442160
  • ENSP00000407130
  • ENST00000540593
  • ENSP00000442228
  • ENST00000555044
  • ENSP00000451763
  • ENST00000615736
  • ENSP00000483073

Symbol
  • APA1
  • APA1
  • APA-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
histone modification site profile
0.81
hub protein
0.79
virus perturbation
0.79
disease perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 122.06   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 169   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 122.06   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 169   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0