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Tdark
ZNF317
Zinc finger protein 317

Protein Summary
Description
May function as a transcription factor. May play an important role in erythroid maturation and lymphoid proliferation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000247956
  • ENSP00000247956
  • ENSG00000130803
  • ENST00000360385
  • ENSP00000353554

Symbol
  • KIAA1588
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.73
transcription factor binding site profile
0.71
cell line
0.59
cell type or tissue
0.59
microRNA
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (16)
TUBA8
Tbio
Novelty:  0.06454549
p_int:  0.999570697
p_ni:  0.000429303
Score:  0.693
Data Source:  BioPlex,STRINGDB
WDR46
Tbio
Novelty:  0.19307408
p_int:  0.999367044
p_ni:  0.000632375
p_wrong:  5.81e-7
Data Source:  BioPlex
RPL7A
Tbio
Novelty:  0.01674027
p_int:  0.998080974
p_ni:  0.001917865
p_wrong:  0.000001161
Data Source:  BioPlex
GNL3
Tbio
Novelty:  0.00886703
p_int:  0.995056514
p_ni:  0.004808441
p_wrong:  0.000135045
Data Source:  BioPlex
RPL26L1
Tdark
Novelty:  0.75408617
p_int:  0.993029525
p_ni:  0.006970475
Score:  0.522
Data Source:  BioPlex,STRINGDB
RSBN1
Tbio
Novelty:  0.1955858
p_int:  0.990477753
p_ni:  0.009447349
p_wrong:  0.000074898
Score:  0.489
Data Source:  BioPlex,STRINGDB
PPAN
Tbio
Novelty:  0.01063709
p_int:  0.957380269
p_ni:  0.03678201
p_wrong:  0.005837721
Data Source:  BioPlex
RBM4
Tbio
Novelty:  0.02034191
p_int:  0.902394743
p_ni:  0.097605257
Data Source:  BioPlex
MRPL30
Tdark
Novelty:  1.03623556
p_int:  0.846763337
p_ni:  0.152927819
p_wrong:  0.000308844
Score:  0.175
Data Source:  BioPlex,STRINGDB
HECTD3
Tdark
Family:  Enzyme
Novelty:  2.20874654
p_int:  0.786362218
p_ni:  0.213637782
Score:  0.173
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suicide behaviour measurement
1
1
1
2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suicide behaviour measurement
1
2
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 317
VGNC:11571
468709
Macaque
zinc finger protein 317
713200
Mouse
MGI:107775
244713
Rat
RGD:1565419
500950
Dog
zinc finger protein 317
VGNC:48694
484975
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 317
Macaque
zinc finger protein 317
Mouse
Rat
Dog
zinc finger protein 317
Publication Statistics
PubMed Score 0.94
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title